Impact of IDNAT on Blood Safety; A Retrospective Study on Prevalence of Infectious Markers and Their Trends amoung Blood Donors at a Tertiary Care Hospital
Journal Title: Indian Journal of Pathology: Research and Practice - Year 2017, Vol 6, Issue 2
Abstract
Introduction: Transfusion transmitted infections (TTI) are major risk factors for blood transfusion. To increase the blood safety IDNAT has been introduced along with compulsory donor screening tests in all NACO assisted blood banks by Government of Karnataka and KSAPS from Dec. 2011. To evaluate the safety benefits of introducing IDNAT and to estimate the seroprevalence of infectious markers TTI and their yearly trends among blood donors, a retrospective studywas conducted at Blood bank of Hassan Institute of Medical sciences, Hassan, Karnataka. Materials and Methods: Blood bank records were reviewed retrospectively from January 2013 to December 2016. Results of mandatory serological tests and NAT Yield cases were compared. Descriptive statistics were used to estimate the prevalence of TTI and to show their yearly trends for four consecutive years. Result: Total numbers of blood units collected during study period were 18,694. Voluntary donors were 69% and Replacement donors were 31%. Out of 176 infective cases detected 23 were serologically non reactive but NAT reactive giving a high NAT yield of 1 in 812 cases.Overall prevalence of TTI was 0.94% and seroprevalence of HIV (0.08% ), HBV ( 0.80%), HCV (0.06% ), Syphilis (0.01% ). An increasing trend of HBV infection and decreasing trend of HIV, HCV were observed among blood donors in these four consecutive years. Conclusion: The present study population showedcomparatively low prevalence of Transfusion transmitted infection and it clearly indicated the benefits of IDNAT screening for the improvement of blood safety.
Authors and Affiliations
Sowmya T. S
Keywords
Related Articles
- EP ID EP463071
- DOI 10.21088/ijprp.2278.148X.6217.26
- Views 83
- Downloads 0
Detection of Seroprevalence and Baseline Titre of Brucella Agglutinins in Blood Donors of Dhule District
Introduction: Brucellosis is a major zoonosis in the developing countries including India. The reported incidence of human brucellosis in endemic areas varies widely, from <0.01 to >200 per lakh population. Despite being...
Histopathological Spectrum of Prostatic Lesions with Special Emphasis on Mimickers of Malignancy
Introduction: Blood transfusion saves millions of life around the world. However knowledge regarding the same in the young and healthy population is not adequate. Aims and Objectives: To study the knowledge, attitude and...
The Bleach Digestion of Sputum: The Method Improves the Detection of Pulmonary Tuberculosis
Introduction: Tuberculosis is a chronic infectious disease caused by mycobacterium tubercular bacilli. It primarily affects lung and it can involve any organ system in the body. There are various methods for detection of...
Nuclear Morphometric Analysis in Fine Needle Aspirates of Breast Neoplasms
Background: Fine needle aspiration cytology (FNAC) is applied as the primary tool for the diagnosis in breast masses because of its ease and rapidity. However, it is a largely subjective tool. The morphological overlap a...
Histopathological Study of Hysterectomy Specimens with or without Adnexa
Introduction: Women worldwide suffer from gynaecological and obstetric disorders that require hysterectomy as a treatment option. Hysterectomy forms the major bulk among the specimens received in our histopathology labor...