Importance of Diarheogenic Escherichia coli (DEC) strains isolated from pediatric patients in a Tertiary care Hospital
Journal Title: IP International Journal of Medical Microbiology and Tropical Diseases - Year 2017, Vol 3, Issue 3
Abstract
ntroduction: Diarrheal disease is a major cause of illness and death among infants and young children worldwide. Among the Escherichia coli (E. coli) causing intestinal diseases, there are six well-described categories Enteroaggregative E. coli (EAEC), Diffusely Adherent E. coli (DAEC), Enteroinvasive E. coli (EIEC), Enteropathogenic E. coli (EPEC), Enterohaemorrhagic E. coli (EHEC) and Enterotoxigenic E. coli (ETEC). Aim: To investigate contribution of different groups of Diarrheagenic E. coli (DEC) in pediatric patients with diarrhea. Materials and Method: This was Prospective laboratory based study approved by Institutional Ethical committee. A total of 100 stool samples were collected from patients admitted with acute diarrhea of 72 hours or less duration in 1- 60 months of age over a period of one year (Sep 2012 to Aug 2013). Escherichia coli were identified by standard Microbiological methods and identified E. coli were transported to National Institute of Salmonela and Escherichia coli center for further Serotyping. Results: The majority of children with diarrhea were in the age group of 7 to 12 months of age (46%). Watery diarrhea was present in 94% of children, followed by vomiting and fever (78%). The study showed that 48 100 children (48%) had diarrhea due to diarrheagenic E. coli. The most prevalent type was ETEC (20.8%) followed by EPEC (16.7%), EHEC (4.1%), and STEC (2.1%). The most prevalent serotypes of ETEC were O27, O23, O169. Among EPEC most prevalent serotypes were O90, O26. The most prevalent EHEC strain found in this study was O71. Conclusion: Study shows that diarrheagenic E. coli is a significant causal agent of diarrheal diseases in pediatric patients and it is a preventable by mere increase in hygiene, education, drinking safe water.
Authors and Affiliations
Ashwini Kacharu Dedwal, Sae Satish Pol, Vaishali Amol Kongre, Renu Satish Bharadwaj
Keywords
Related Articles
- EP ID EP305806
- DOI 10.18231/2455-6807.2017.0032
- Views 91
- Downloads 0
Study of Vulvo-Vaginal Candidiasis among Patients Visiting Obstetrics and Gynecology Department in a Tertiary Care Centre
Background: Vulvovaginitis is a common day to day problem in gynecological practice. Candida albicans is the commonest infectious cause. An estimated 75% of women have at least one episode of Vulvo-vaginal Candidiasis an...
Direct reporting cefazolin from VITEKļ 2 for E. coli, K. pneumoniae and P. mirabilis isolated from urine cultures using new CLSI interpretations
Background: In recent years, Clinical and Laboratory Standard Institute (CLSI) has recommended a series breakpoint changes for cefazolin, including testing it as a surrogate agent for oral cephalosporins for treating unc...
Study of intestinal parasites in food handlers in a tertiary care centre in Kanchipuram
nbspIntroduction Food handlers with poor hygiene working in food establishment areas have been reported as a potential source of helminths amp protozoans all over the world Individuals with symptoms of parasitic infectio...
Antibiotic resistance pattern of urinary isolates in a Rural Medical College of Maharashtra
Objective: To determine resistance pattern of urinary isolates in a rural medical college of Maharashtra. Methods: Urine samples were collected using midstream clean catch method in clinically diagnosed UTI cases from au...
Urinary E.coli isolates in tertiary care centre of south Kerala: Antibiogram and ESBL detection by phenotypic confirmatory disc diffusion testing
Gram negative bacterial infections are the most important cause of Urinary Tract Infections UTI in India Ecoli being the most common isolate and has been resistant to commonly used antibioticsMaterials and Methods This s...