In vitro antibacterial activity of various tissue types of Dumortiera hirsuta (Sw) Nees from different altitudes of eastern Himalaya

Journal Title: Asian Pacific Journal of Tropical Disease - Year 2012, Vol 2, Issue 0

Abstract

Objective: To study the antibacterial activity of methanol and ethanol extracts of vegetative, male sexual and female sexual reproductive thalli of the bryophyte Dumortiera hirsuta collected from five different altitudes of eastern Himalaya against some human pathogenic bacteria. Methods: Well diffusion method, determination of minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were carried out against strains of human pathogenic bacteria. Results: Different tissue types of the bryophyte collected from various altitudes have shown to inhibit the human pathogenic bacterial strains in vitro. Maximum antibacterial activity was noted against S. marcescens (ATCC 13880) for both the 80% methanolic and ethanolic extracts of both the vegetative and the reproductive thalli. The extracts of the reproductive thallus showed less antibacterial activity than that of the vegetative thallus. Specimens collected from higher altitude showed slightly lesser antibacterial activity than their lower altitude counterparts. Conclusions: Antibiotic activity was noted to be dependent on solvent system used for extraction, altitude and tissue type. Analyses of extracts may yield some bioactive molecule responsible for antibacterial efficacy of the bryophyte.

Authors and Affiliations

Keywords

Related Articles

The association of C r y p t o s p o r i d i u m from three different points of Balok River and Kuantan River by using physico-chemical and heavy metal assessments

Objective: To detect the occurrence of Cryptosporidium oocysts and to assess the physicochemical and heavy metal parameters in two main rivers in Kuantan. Methods: Water samples were collected at three sampling points pe...

Management of fever among under-fives and utility of malaria rapid diagnostic test under reduced malaria burden in Rufii District, Southeastern Tanzania

Objective: To investigate case management of fever among under-fives, performance and utility of malaria rapid diagnostic test (mRDT) under reduced malaria burden in Rufiji District, Southeastern Tanzania. Methods: A qua...

Development and Characterization of Mouth Dissolving Tablet of Zolmitriptan

Objective: To formulate and Characterize Mouth Dissolving Tablet of Zolmitriptan to produce the intended benefits. Methods: Tablets were prepared using a direct compression method employing superdisintegrants such as Kyr...

Efficacy and toxicological evaluation of Coccinia grandis (Cucurbitaceae) extract in male Wistar rats

Objective: To investigate the oral antihyperglycemic effect of aqueous leaf extract of Coccinia grandis (L.) (Cucurbitaceae) along with toxicological effects in alloxan induced diabetic and healthy Wistar rats. Methods:...

Investigation of hemorrhagic fever viruses inside wild populations of ticks: One of the pioneer studies in Saudi Arabia

Objective: To screen hemorrhagic fever viruses inside wild populations of ticks collected from Riyadh, Saudi Arabia between January and March 2016. Methods: Ticks were identified depending on their morphological features...

Download PDF file
  • EP ID EP233276
  • DOI 10.1016/S2222-1808(12)60167-4
  • Views 64
  • Downloads 0

How To Cite

(2012). In vitro antibacterial activity of various tissue types of Dumortiera hirsuta (Sw) Nees from different altitudes of eastern Himalaya. Asian Pacific Journal of Tropical Disease, 2(0), 285-290. https://europub.co.uk/articles/-A-233276