In Vitro Antimicrobial Activity of Chlorine Effervescent Tablets against Some Pathogenic Bacteria and Fungi
Journal Title: Open Access Journal of Pharmaceutical Research - Year 2020, Vol 4, Issue 3
Abstract
Objectives: The objective of the present study was to evaluate the antimicrobial activity of available choline (sodium dichloroisocyanurate (NaDCC) ) effervescent tablet solutions. Methods: Four bacteria and one fungi were used such as Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Candia albican. Strains were selected to evaluate the antimicrobial activity of the sodium dichloroisocyanurate solutions by the agar wells diffusion assay. Results: The results were significantly different among the tested solutions: 10000 ppm NaDCC solution produced the highest a high antimicrobial activity with Escherichia coli compared with liquid bleach (Clorox®);.,while another organisms such as Pseudomonas and candida were in a close effective compared with commercial product and 2000 ppm NaDCC solution showed the lowest zones of inhibition, so The antimicrobial activity of NaDCC that was prepared in the lab was the same effective with commercial product was used as standard to compare with and its concentration was 5% (50000 ppm). Conclusion: Even if all tested irrigating solution possessed antibacterial activity versus all tested bacterial strains, 3000 ppm NaDCC solution with liquid bleach 5% (Clorox®), and 1000ppm NaDCC sol. showed lower in vitro efficacy than 10000 ppm NaDCC solution.
Authors and Affiliations
Al- Nowihi M*, Al-Asbahi G, Faisal A and Al-Absi M
Keywords
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- EP ID EP748468
- DOI 10.23880/oajpr-16000208
- Views 29
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