In-vitro Antioxidant activities of hydro alcoholic extracts of Trigonella foenum-graecum seeds, Cinnamomum verum bark and Carica papaya leaves and seeds
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2014, Vol 2, Issue 6
Abstract
Background: Oxidative stress and free radical damage have been implicated in the pathogenesis of various diseases like cancer. Apart from the human body’s antioxidant mechanisms several dietary constituents could aid in mitigating oxidative stress. Aim and objectives: To assess the in-vitro antioxidant activity of hydro alcoholic extracts of Trigonella foenum graecum seeds, Cinnamomum verum bark and CO.2 strain Carica papaya male leaves, female leaves and seed extracts. Materials and methods: Hydroalcoholic extracts of Trigonella foenum graecum seeds, Cinnamomum verum bark, CO.2 strain Carica papaya male leaves, female leaves and seeds were prepared and in-vitro antioxidant activities were assessed by Total antioxidant activity assay, Reducing power assay, Nitric oxide scavenging activity assay, DPPH radical scavenging assay and Superoxide radical scavenging activity assay. Ascorbic acid and quercetin were used as standards. The experiments were done in triplicates and the results were subjected to statistical analysis. Results: The results obtained indicated that all the herbal extracts studied, showed significant antioxidant activity. Summary and Conclusion: The results of our study demonstrated that all the herbs studied exerted antioxidant effects through different mechanisms. Hence a polyherbal formulation comprising of all the above herbal extracts would be a good adjuvant in prevention and management of various diseases including cancer.
Authors and Affiliations
Saranya. V, Malathi. N, Chamundeeswari. D, D. Sakthisekaran
Keywords
Related Articles
- EP ID EP33254
- DOI -
- Views 249
- Downloads 0
Preclinical evaluation of antispermatogenic activity of Curcuma amada on cell phone radiation induced infertility in rats
To study the ability of the electromagnetic signals emitted by cellular mobile telephony to affect the biological function of living organisms and mobile radiation exposures are changes in the structure and functional...
Preliminary phytochemical and toxicity studies of Oenothera biennis
The present investigation was carried out to evaluate the safety of methanol extract from leaves of Oenothera biennis by determining its potential toxicity after acute and sub acute administration in mice. For the acut...
In-vitro callus regeneration and rhizogenesis in Diploknema butyracea: a valuable tree borne oilseed
In-vitro callus regeneration and rhizogenesis is achieved from leaf segments of mature tree of Diploknema butyracea (Roxb.) Lam. Explants sterilization was standardized using 0.1% HgCl2 for 3 minutes and NaOCl (40%) fo...
DESIGN AND DEVELOPMENT OF AMLODIPINE BESYLATE FAST DISSOLVING TABLETS BY USING NATURAL SUPERDISINTEGRANTS
Amlodipine besylate is a long-acting calcium channel blocker used in the treatment of chronic stable angina, vasospastic angina and hypertension. Amlodipine besylate is a sparingly soluble orally administered drug and...
Formulation and evaluation of Orodispesible tablets of Aripiprazole tablets
The aim of present work was to prepare mouth dissolving tablets of Aripipazole tablets, used it is atypical antipsychotic medication used for the treatment of schizophrenia. It has also recently received FDA approval fo...