In-vitro Antioxidant activities of hydro alcoholic extracts of Trigonella foenum-graecum seeds, Cinnamomum verum bark and Carica papaya leaves and seeds
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2014, Vol 2, Issue 6
Abstract
Background: Oxidative stress and free radical damage have been implicated in the pathogenesis of various diseases like cancer. Apart from the human body’s antioxidant mechanisms several dietary constituents could aid in mitigating oxidative stress. Aim and objectives: To assess the in-vitro antioxidant activity of hydro alcoholic extracts of Trigonella foenum graecum seeds, Cinnamomum verum bark and CO.2 strain Carica papaya male leaves, female leaves and seed extracts. Materials and methods: Hydroalcoholic extracts of Trigonella foenum graecum seeds, Cinnamomum verum bark, CO.2 strain Carica papaya male leaves, female leaves and seeds were prepared and in-vitro antioxidant activities were assessed by Total antioxidant activity assay, Reducing power assay, Nitric oxide scavenging activity assay, DPPH radical scavenging assay and Superoxide radical scavenging activity assay. Ascorbic acid and quercetin were used as standards. The experiments were done in triplicates and the results were subjected to statistical analysis. Results: The results obtained indicated that all the herbal extracts studied, showed significant antioxidant activity. Summary and Conclusion: The results of our study demonstrated that all the herbs studied exerted antioxidant effects through different mechanisms. Hence a polyherbal formulation comprising of all the above herbal extracts would be a good adjuvant in prevention and management of various diseases including cancer.
Authors and Affiliations
Saranya. V, Malathi. N, Chamundeeswari. D, D. Sakthisekaran
Keywords
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