IN VITRO INVESTIGATION OF ANTIBACTERIAL AND ANTILEISHMANIAL ACTIVITIES OF GUM-RESIN OF BOSWELLIA SERRATA USING (0.5%) DMSO SOLUTION AS AN ALTERNATIVE SOLVENT FOR EXTRACTION
Journal Title: WORLD JOURNAL PHARMACY AND PHARMACEUTICAL SCIENCE - Year 2017, Vol 6, Issue 9
Abstract
Boswellia serrata belongs to the family Burseraceae, is a plant that produces frankincense. The plant is native to India and extends to Pakistan. The tree yields oleo-gum- resin which has been used for a variety of therapeutic purposes such as cancer, inflammation, arthritis, asthma, psoriasis, colitis, Crohn’s Disease, and hyperlipedimia, antibacterial and antifungal activities. The current study investigated the antibacterial (S. aureus and E. coli) and antileishmanial (L.tropica and L. donovani) activities of B. serrata aqueous crude extract using (0.5%) DMSO solvent for extraction. The phytochemical analysis of crude extract was positive for saponin only. The extract failed to inhibit bacterial growth on Muller- Hinton agar plate. Lower concentrations (5%, 2.5% and 1.25%) of extract showed antileishmanial activity against two species of Leishmania. The (10%) concentration lacked antileishmanial activity. The study concludes that B. serrate gum- resin has a potential antileishmanial activity against two species of Leishmania using a safe concentration of (0.5%) DMSO as an alternative aqueous solvent for methanol extracting gum- resins.
Authors and Affiliations
Dr. Niran A. H. Al-Ogaili
Keywords
Related Articles
- EP ID EP618644
- DOI -
- Views 150
- Downloads 0
EVALUATION OF CAMPYLOBACTER CONTAMINTION IN POULTRY HOUSES AND POULTRY SLAUGHTERHOUSES IN BAHRI LOCALITY – SUDAN
This study was carried out during the period from April to June 2017 in Bahri locality, Sudan. The overall objective of this study is to evaluate the hygienic biosecurity practices designed to control campylobacter conta...
A COMPARITIVE STUDY ON NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD)-REVIEW
Non-Alcoholic Fatty Liver Disease (NAFLD) is a widespread liver disorder in the world in both developed and developing countries. It is the condition where the accumulation of lipids/fats in the liver occurs, primarily t...
REVIEW ON MICROEMULSION AN UNCONVENTIONAL DRUG DELIVERY SYSTEM
The concept of a microemulsion was first introduced in the 1940s to describe transparent single-phase systems generated by titrating a milky emulsion with hexanol. Since their first description, microemulsions have been...
SYNTHESIS, CHARACTERISATION, ANTIMICROBIAL EVALUATION OF 2-HYDROXY PHENYL THIAZOLIDINE-4-ONE DERIVATIVE
A new series of N-(2-(2-hydroxyphenyl)-4-oxothiazolidin-3-yl) isonicotinamide derivatives were synthesized by the reaction of schiff base (Isoniazid and 2 hydroxy benzaldehyde) with mercaptoacetic acid respectively. The...
CONCEPTUAL STUDY OF SHEETAPITTA WITH SPECIAL REFERENCE TO URTICARIA
Ayurveda is the science of life providing guidelines on ideal daily and seasonal routines, diet, behaviour and proper use of senses for healthy and happy life. It suggests health as the balanced and dynamic integration b...