In vivo analgesic activity of petroleum ether extract of boswellia ovalifoliolata linn. Leaves
Journal Title: International Journal of Research in Pharmacology & Pharmacotherapeutics (IJRPP) - Year 2012, Vol 1, Issue 1
Abstract
Boswellia ovalifoliolata Linn. (Family: Burseraceae) Leaves were extracted in petroleum ether (60°-80°C) to evaluate for centrally acting analgesic potential using tail immersion and peripheral pharmacological actions using acetic acid induced writhing test in mice. Boswellia ovalifoliolata Linn. extracts were found to have been significant (p<0.05) analgesic activity at the oral dose of 200 & 400 mg/kg b. wt., in the tested models. In tail immersion test Boswellia ovalifoliolata Linn. extracts showed increased tail withdrawal time whereas in acetic acid induced writhing test Boswellia ovalifoliolata Linn. extracts showed reduced number of writhes at two dose levels, which are significant (p<0.05) compared to control. The results obtained support the use of leaves of Boswellia ovalifoliolata Linn. extracts in painful conditions acting both centrally and peripherally
Authors and Affiliations
B. Deepak Kumar
Keywords
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