ІНДЕКС ПРОЛІФЕРАЦІЇ Kі-67 У ХВОРИХ НА ПЕРФОРАЦІЮ ПЕПТИЧНОЇ ВИРАЗКИ ТА СТАНУ ПЕРІУЛЬЦЕРОЗНОЇ ДІЛЯНКИ
Journal Title: World Science - Year 2017, Vol 2, Issue 9
Abstract
The results of surgical treatment of 204 patients with perforation of pyloroduodenal ulcer have been analyzed. To study the proliferative activity of cells and to determine the index of proliferation in the periulcerosis region, an immunohistochemical method for investigating the expression of Ki-67 antigen was used. It was established that in the ulcerative defect of caudal perforation ulcers, the reparative processes are low and very low. It is extremely undesirable to suture these ulcers due to poor healing and a high risk of insufficiency of sutures in the early postoperative period and recurrence of ulcers in the long term after surgery. Taking into account the obtained data, the choice of surgical tactics is the carving of cranial perforated peptic ulcers. In the absence of causal infiltration, immunohistochemical studies have shown high reparative capacity of tissues in the area of the ulcerative defect, which makes it possible to recommend the perforation of the ears as a selection operation for these perforated ulcers. Laparoscopic intervention with complicated peptic ulcer is a safe and effective method of treatment. Advantages of laparoscopic access - increase of comfort for the patient, their early return to daily activity.
Authors and Affiliations
Д. О. Смецков, Т. П. Яворська, Н. М. Гончарова
Keywords
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