Indian Lettuce Extract as Feed Additive Enhances Immunological Parameters in Mono-Sex Nile Tilapia against Aeromonas hydrophila
Journal Title: Journal of Pharmaceutical Research International - Year 2015, Vol 5, Issue 5
Abstract
Aims: The present study evaluated the efficacy of dietary doses of Lactuca indica extract on immunological parameters and disease resistance against Aeromonas hydrophila infection in mono-sex Nile tilapia, Oreochromis niloticus. Place and Duration: This experiment was performed in the Laboratory of Fisheries and Marine Bioscience (FMB), Jessore University of Science and Technology (JUST), on July to December 2013. Methodology: Lactuca indica extract preparations, harbal diet preparations, Aeromonas hydrophila Isolation, specific and non-specific immunological assays (following phagocytic activity and serum agglutination) and challenge test were performed. Result: A. hydrophila is a more drastic disease producing and common cause of bacterial haemorrhagic septicaemia, it is a gram-negative, non spore-forming, rod-shaped, yellowish colony forming bacteria. Fishes were fed with L. indica extract at 0%, 0.5%, 1%, 1.5% and 2.0%; among those 2.0% showed highest significant responses in phagocytic activity, specific growth rate, specific and non-specific immune responses on week 2 and 4 compared to control diet whereas the changes did not manifest on first week. All groups fishes were injected intraperiotonaly (i.p.) with A. hydrophila at 3.5×10-7 CFU ml-1 for analyzing cumulative mortality on 30th day of feeding. L. indica enriched diet at 2.0% level resulted in lowest mortality (20%) indicating highest protection (Relative Percent Survival, RPS 75%) from A. hydrophila infection than 0.5%, 1.0% and 1.5% doses diet that resulted 72%, 56% and 32% mortalities respectively. 2% dose also showed highest growth compare to other doses. Conclusion: The results suggest that the dietary supplementation of L. indica extract stimulates immunostimulants, reduce mortality and increases disease resistance in O. niloticus against A. hydrophila infection.
Authors and Affiliations
Farzana Yeasmin, Md. Mer Mosharraf Hossain, Aisha Khatun, Mohammad Zillur Rahman, Md. Eftakher Alam
Keywords
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- EP ID EP344351
- DOI 10.9734/BJPR/2015/15436
- Views 107
- Downloads 0
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