Induced pluripotent stem cells in infections
Journal Title: International Journal of Blood Transfusion and Immunohematology - Year 2015, Vol 5, Issue 1
Abstract
Aims: Blood transfusion is an essential management to save patients life in health care system. Blood is a potential source of transmitted diseases which make the safety of blood products important issue in laboratory medicine. Investigations of transfusion-transmitted infections (TTI), especially hepatitis viruses and acquired immunodeficiency virus, are essential in all blood bank policies. Several methods were applied to screen blood products for hepatitis B and hepatitis C viruses and acquired immunodeficiency virus. Methods: Blood donor's samples for one year were collected and examined for hepatitis viruses and acquired immunodeficiency virus by using serological and nucleic acid testing (NAT). Results: Comparative study showed that NAT is more specific than serologic screening testing for both hepatitis C virus and acquired immunodeficiency virus. However, NAT and serological tests are required to increase the safety of blood components from hepatitis B virus transmission. Conclusion: This study is an attempt to evaluate the effectiveness of introducing NAT for examination of blood components. National-wide study is required to evaluate the policy of blood screening program.
Authors and Affiliations
Anubha Singh, Deepak Kumar Singh, Usha Bhoria
Bombay blood phenotype: Laboratory detection and transfusions recommendations
Four main blood types routinely identified today are A, B, AB, and O. Universal donors have type "O" blood, and have no "A" or "B" antigens. In turn, no blood reactions will occur in recipients. Conversely, universal rec...
A new look at an old case: An auto-anti-P with pseudo-LKE activity
Aims: LKE is a high-incidence, minor RBC glycosphingolipid, related to both Pk and P antigens. Approximately 1% individuals are LKE-negative. However, antibodies against LKE are rare, with only six cases mentioned in lit...
Induced pluripotent stem cells in infections
Aims: Blood transfusion is an essential management to save patients life in health care system. Blood is a potential source of transmitted diseases which make the safety of blood products important issue in laboratory me...
Preparation of red cell concentrates in low-income countries: Efficacy of whole blood settling method by simple gravity in Burkina Faso
Aim: This study aims to describe the characteristics of the red cell concentrates (RCCs) produced by whole blood settling in Burkina Faso. Methods: We conducted a cross-sectional study in the blood centers of Ouagadougo...
Assessment of donor deferral rates and deferral reasons at the Namibia blood transfusion services
Aims: Despite the need to recruit and retain more blood donors, some are deferred from donating to ensure their safety and that of recipients is maintained. Examination of donor deferrals provides insights into how donor...