Influence of Altiazem PP-180 on Hemodynamic Parameters in Arterial Hypertension Patients under Outpatient Conditions
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2017, Vol 6, Issue 10
Abstract
The aim of this research work is to study the effect of altiazem PP-180 on hemodynamic parameters in 78 II-degree arterial hypertension patients under outpatient conditions. Hemodynamic effect of altiazem PP-180 hypotensive action was successfully observed at 07.00 a.m., 10.00 a.m. and 10.00 p.m. intake time, with normal patients’ routine. Altiazem PP-180 causes a distinct hypotensive effect in II-degree arterial hypertension patients when used under outpatient conditions at different times of a day both fxed or random. The most productive hemodynamic effect of altiazem PP-180 hypotensive action can be observed when taken at 07.00 a.m., 10.00 a.m. and 10.00 p.m. provided that a normal work/rest routine is kept. When administered at 07.00 a.m., 10.00 a.m. and 10.00 p.m., altiazem PP-180 causes substantial decrease of peripheral vascular resistance, end-diastolic and end-systolic volumes. Hypotensive effect of altiazem PP-180, when administered at 01.00, 04.00 and 07.00 p.m. as well as at non-fxed times of day shows a less favourable hemodynamic effect: reduced cardiac output associated with total and peripheral vascular resistance index.
Authors and Affiliations
GR Zhakiyeva| Associate Professor and HOD, General Practice of Internship and Postgraduate Training, West Kazakhstan Marat Ospanov State Medical University, Aktobe, Kazakhstan Corresponding e-mail: gulzhahan.zhakieva@list.ru, LM Tulegenova| Professor, Department of General Practice of Internship and Postgraduate Training, West Kazakhstan Marat Ospanov State Medical University, Aktobe, Kazakhstan, NZ Ibragimova| Assistant Professor, Department of General Practice of Internship and Postgraduate Training, West Kazakhstan Marat Ospanov State Medical University, Aktobe, Kazakhstan, SM Kelimberdiyev| Professor, Department of General Practice of Internship and Postgraduate Training, West Kazakhstan Marat Ospanov State Medical University, Aktobe, Kazakhstan, KK Tokbayeva| Assistant Professor, Department of General Practice of Internship and Postgraduate Training, West Kazakhstan Marat Ospanov State Medical University, Aktobe, Kazakhstan
Keywords
Related Articles
- EP ID EP12479
- DOI -
- Views 374
- Downloads 14
A comparative profile analysis of neuropsychological functioning in patients with schizophrenia and bipolar and normal group based on stroop test and Benetton visual retention test
The relation between brain and mind is quite evident. Neuropsychological instruments have made considerable contributions in evaluating cognitive functions among healthy individuals and those patients suffering from ps...
ELECTRODERMAL ACTIVITY: APPLICATIONS IN PERIOPERATIVE CARE
Background: Electrodermal activity is originated from the activation of sweat glands in the skin in response to stress or other stimuli and thought to reflect the activity of the sympathetic nervous system, or physiolog...
The study of MS patients’ life style referred to MS Association [Tehran City, 2008]
Multiple sclerosis [M.S] is one of the common autoimmune diseases that effects on central nervous system. It is unpredictable and cause to changes in life style. M.S progresses to inability. There is a close relation be...
CLINICAL PATTERN AND EFFECT OF CO-MORBIDITIES IN THE ETIOPATHOGENESIS OF INCISIONAL HERNIAS
Background: Incisional hernia is a common iatrogenic complication of abdominal surgery and is a cause of unwanted morbidity. The study was reported for the first time from Republic of Mauritius. Aims & Objectives: The...
Antioxidant Effects of Green-Tea on biochemical and Histopathological Changes of liver in Male Rats Poisoned by Malathion Insecticide
Malathion is an organophosphate pesticide which is widely used in agriculture, veterinary and industries. Oxidative stress has been identified as one of Malathion’s main molecular mechanisms of action in plasma, liver...