INSILICO COMPARATIVE STUDY OF VIRAL GENOMES OF PARVOVIRIDAE
Journal Title: Int J of Pharm Rev& Res - Year 2014, Vol 4, Issue 2
Abstract
The Current Research deals with comparative study and functional similarities of viral genomes of the family parvoviridae. Parvoviridae is a viral family of single stranded DNA viruses with some identical proteins for the infecting the animals. Current study reveals the similarity of genomes and protein sequences of different viral species namely Adeno associated virus, Bovine adeno associated virus, Canine minute virus, Minute virus of mice, Mouse parvo virus, Muscovy duck parvo virus. The above mentioned six species of single stranded DNA animal viruses, those with genomic similarity with each other and also some identical proteins were isolated. The Open Reading Frame (ORF) of these genomes is encoding for the production of some specific proteins such as replication catalytic domain, capsid protein, Non structural protein and Coat protein. From this research, it was found that the similar infectious and replicative proteins present in the several species of viral family parvoviridae.
Authors and Affiliations
A. Sumathi , L. Surendran
Keywords
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