Intrathecal Fentanyl as an Adjuvant to Hyperbaric Bupivacaine in Lower Abdominal Surgeries: A Placebo Controlled Randomised Study

Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2019, Vol 6, Issue 1

Abstract

Aim: The aim of our study was to evaluate the efficacy of intrathecal fentanyl as an adjuvant to bupivacaine on the block characteristics, hemodynamic stability and side effects in patients undergoing lower abdominal surgeries. Methods: Sixty patients aged between 18-60 yrs, belonging to ASA I and II posted for elective lower abdominal surgeries under spinal anaesthesiawere recruited for the study. Patients were randomly divided into two groups of thirty each. One group received 2.5 ml of 0.5% Inj. bupivacaine with 0.5 ml of fentanyl (Group FB) and the other group received 2.5 ml of 0.5% Inj. bupivacaine with 0.5 ml of normal saline (Group B). Patients were monitored for onset, duration and quality of sensory and motor block, duration of analgesia, highest dermatomal level, hemodynamic parameters and side effects. Results: Onset of sensory block, motor block, time to reach highest dermatomal level duration of motor block was comparable between the groups. Duration of sensory block and two segment regression was prolonged in group FB compared to Group B which was statistically significant (p < 0.001). Hemodynamic stability was maintained throughout intra and post-operative period in Group FB compared to Group B. Incidence of pruritis was higher in Group FB compared to Group B which was statistically significant ( p< 0.001). Conclusion: Fentanyl as an adjuvant to bupivacaine provided sufficient post-operative analgesia with hemodynamic stability.

Authors and Affiliations

Naveen Kumar P

Keywords

Related Articles

To Compare The Haemodynamic Resopnses and Adequacy of Ventilation Between Laryngoscopic Endotracheal Intubation and Laryngeal Mask Airway Classic Insertion in Short Surgical Procedures Under General Anaesthesia with Muscle Relaxation

The haemodynamic response associated with laryngoscopy and tracheal intubation may be harmful to certain patients. The laryngeal mask airway (LMA) avoids the need for laryngoscopy and allows positive pressure ventilation...

Comparative Study of Intravenous Ondansetron and Dexamethasone for Amelioration of Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy

Background: Postoperative nausea and vomiting (PONV) is considered most unpleasant experience by the patients in postoperative period. In particular, following laparoscopic procedures the incidence of PONV is very high....

A Study of First Aid Knowledge Acquired by Pre-Hospital Trauma Technician Trainees in a Tertiary Care Hospital: A Retrospective Observational Study

Aim: PreĀ­hospital trauma students first aid skills assessment at various stages of training. Design: Retrospective observational study. Material and Methods: In our study, First Aid skills and knowledge were assessed of...

Comparative Study of Intravenous Lignocaine and Sublingual Nitroglycerine to Attenuate Stress Response to Laryngoscopy

Laryngoscopy and intubation is associated with a reflex sympathetic pressor response resulting in elevated heart rate (HR) and blood pressures (BP). This may prove detrimental in high risk patients and may be in normal...

A Study on the Efficacy of Ketamine Given Intrathecallyas A Spinal Anesthetic Agent

Ketamine a phencyclidine derivative with potent analgesic properties possesses few advantages over the other local anesthetics as it tends to stimulate the cardiovascular system and maintains the respiratory response to...

Download PDF file
  • EP ID EP601146
  • DOI 10.21088/ijaa.2349.8471.6119.40
  • Views 45
  • Downloads 0

How To Cite

Naveen Kumar P (2019). Intrathecal Fentanyl as an Adjuvant to Hyperbaric Bupivacaine in Lower Abdominal Surgeries: A Placebo Controlled Randomised Study. Indian Journal of Anesthesia and Analgesia, 6(1), 283-286. https://europub.co.uk/articles/-A-601146