Nalbuphine as an Intrathecal Adjuvant is a Good Alternative to Fentany l
Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2017, Vol 4, Issue 1
Abstract
Background: 0.5% Bupivacaine used in subarachnoid block provides about 3 hours of analgesia. Opioids morphine and Fentanyl are used as adjuvant to produce extended postoperative analgesia. Nalbuphine is an agonist antagonist and does not require a narcotic license, which is a must for procuring other opiods. This study was carried out to evaluate the efficacy of Nalbuphine versus Fentanyl as intrathecal adjuvant. Material and Methods: Hundred ASA 13 patients posted for elective Total Abdominal Hysterectomy were included in this study and were randomly divided into two groups of fifty each. Group FB received 15mg of 0.5% Bupivacaine and 25 mcg of Fentanyl. Group NB received 15mg 0.5% Bupivacaine and 1mg Nalbuphine. Results: The onset of sensory blockade, time to attain peak sensory block and complete motor block was significantly faster in Group FB(p<0.001). The duration of motor block was comparable in both the groups. The time for sensory block to regress by two segments was significantly longer in Group NB, 97.72±9.50 minutes, than in Group FB, 88.88±9.48 minutes. The time to first analgesic requirement in Group NB was 460.78±77.98 minutes compared to 283.44±78.97 minutes in Group FB(p<0.001). No statistical difference was seen in terms of adverse effects. Conclusion: Time for sensory level to regress by two segments and the post operative analgesia time is longer with Nalbuphine. So, Nalbuphine is a good adjuvant in spinal anaesthesia especially in centres without narcotics license.
Authors and Affiliations
Swati Bisht
Keywords
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- EP ID EP462325
- DOI 10.21088/ijaa.2349.8471.4117.14
- Views 146
- Downloads 0
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