Invention of Analgesic and Anti-Inflammatory Activity of Ethanolic Extract of Mimosa Pudica Linn Leaves.
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2012, Vol 1, Issue 1
Abstract
The ethanolic extract of the leaves of Mimosa pudica at the doses of 200 and 400mg/kg was tested for anti-inflammatory and analgesic activity. The extract produced dose dependent and significant inhibition of carrageenan induced paw oedema.The analgesic activity was found to be more significant on the acetic acid induced writhing model (p<0.001) than the tail flick model (p<0.001). So the extract inhibits predominantly the peripheral mechanism. The presence of flavonoids in the ethanolic extract may be contributory to its analgesic and anti-inflammatory activity.
Authors and Affiliations
Dr. Chandrashekar D. K. *| Department of Microbiology, MRMC, Gulbarga, Dr. Deepak M. Manthale| Department of Microbiology, MRMC, Gulbarga
Keywords
Related Articles
- EP ID EP1500
- DOI -
- Views 630
- Downloads 29
INVITRO ANTIOXIDANT ACTIVITY AND HPTLC ANALYSIS OF WITHANIA SOMNIFERA
Withania somnifera is a well known medicinal plant having wide range of medicinal properties. HAEWS, MEWS and AEWS were comparatively standardized for the content of Withanolide D by HPTLC. All the samples were screened...
Impact of Calcium-Vitamin D Supplements on the Dissolution Pattern of Ranitidine Hydrochloride Tablets: An in vitro Dissolution Study using UV Spectroscopy
The objective of this study was to evaluate the impact of Calcium-Vitamin D supplement formulations on the dissolution pattern of different Ranitidine Hydrochloride tablet formulations. This was an in-vitro dissolution s...
UTILITY OF ASSESSMENT SERUM LEVELS OF VEGF, bFGF AND PDGF-BB AS SUGGESTED ANGIOGENESIS BIOMARKERS PANEL TOOL IN PATIENTS WITH BREAST CANCER
Introduction: Breast cancer is the commonest cause of cancer death in women worldwide. A shift in the angiogenic balance allows the up-regulation of several pro-angiogenic factors, which by ways of mutual interactions s...
ANTIDIABETIC ACTIVITY OF 2-AMINO-(5-FLUORO-2-OXOINDOLIN-3-YLIDENE) BENZOXAZOLE-5-CARBOHYDRAZIDE IN RATS
The present study was designed to evaluate the antidiabetic activity of new indole derivatives i.e 2-Amino-(5-fluoro-2-oxoindolin-3-ylidene) benzoxazole-5-carbohydrazide against alloxan induced diabetic rats. Alloxan (12...
MicroRNAs in health and disease; a review of its multifaceted roles
A new class of noncoding small RNAs, called microRNAs (miRNAs), has emerged as important regulators in biological processes. The important role of miRNAs in inflammation and immune response is highlighted by studies in w...