Investigating the Relationship Between Impulsivity and Deficit in Executive Functions of Brain in Patients with Substance Use Disorder

Abstract

Introduction: In recent years, research into the biological foundations of addiction has attracted the attention of many researchers. Researchers found that substance use is the result of greater activity of the brain behavioral activation system which is in turn associated with impulsivity and risk taking. Neurological factors such as impairment of executive functions are also of great importance. This study aimed to investigate the relationship between impulsive behaviors and deficit in executive functions of brain in addicts. Methods and Materials: This research was a cross sectional study. 120 patients with substance use disorder referred to addiction treatment centers were randomly selected. For data collecting, questionnaires were completed before taking medication. Different functions were measured: impulsivity by Barrat`s Impulsivity Scale, working memory by Memory span test and attention by Stroop test. For data analysis, Pearson correlation was used. Findings: data analysis showed a significant statistical correlation between working memory and attention with impulsivity, but this correlation was in negative direction. Conclusion: Executive functions such as working memory and attention are important structures that play a central role in directing and normalizing behavior. These functions are defined as high-level cognitive processes that are involved in the planning, initiation, and regulation of targeted behavior. Deficit in these structures leads to impulsivity and risk taking behaviors. These findings can help experts for the use of proper methods for prevention and expansion of helpful treatments of addiction.

Authors and Affiliations

Rajabpour Mojtaba, Gohari Ali, Eghbali Ghahyazi Hamid, Sheybani Hosein

Keywords

Related Articles

Neuro-Restorative Effect of Sertoli Cell Transplants in a Rat Model of Amyloid Beta Toxicity

Alzheimer’s disease (AD) is a degenerative nerve disease which adversely affects memory and learning skills. Currently, there is no disease-modifying therapeutic approach for AD. However, a growing body of literature s...

Evaluation of Neuronal Repair Process on Focal Demyelination Model of Multiple Sclerosis in Rat

Multiple sclerosis (MS) is one of the most autoimmune neurological and inflammatory disease in worldwide. Demyelination and disturbance of action potential conductance are regarded as main signs of MS disease. Hesperet...

Curcumin-Loaded Niosome Particle-Induced Cell Cycle Arrest and Apoptosis in Brain Cancer Stem Cell

Background: Using a novel curcumin-loaded niosome particle (CM-NP), the present study was designed to evaluate the effect of curcumin on human glioblastoma stem-like cells (GSCs). CM-NP has a diameter of ~60 nm and a ze...

Visual Functions in Children with Dyslexia

Dyslexia or difficulty in reading is one of the most common type of learning disabilities. Underlying mechanisms of this disability are not fully understood and are debated for a long time. Although deficits in magnocel...

The Role of Nitric Oxide (NO) in Shell of Left Nucleu Accumbense on Learning and Memory in Stress Condition Induced by Electrical Foot Shock in Male Wistar Rats

Introduction: Any extrinsic or intrinsic stimulus that evokes a biological response is known as stress. In this case, the body's homeostatic mechanisms are activated to compensate for the conditions created with prolong...

Download PDF file
  • EP ID EP677957
  • DOI 10.29088/GCNR-2020.48
  • Views 193
  • Downloads 4

How To Cite

Rajabpour Mojtaba, Gohari Ali, Eghbali Ghahyazi Hamid, Sheybani Hosein (2020). Investigating the Relationship Between Impulsivity and Deficit in Executive Functions of Brain in Patients with Substance Use Disorder. The 1st Annual Meeting of Georgian Center for Neuroscience Research, 2(20), -. https://europub.co.uk/articles/-A-677957