INVESTIGATION OF THE ANTIBIOTIC RESISTANCE: THE CASE OF BUU DIEN GENERAL HOSPITAL IN HO CHI MINH CITY
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2019, Vol 11, Issue 7
Abstract
Objective: In Vietnam, antibiotic resistance has been gained the attention of medical professionals in antibiotic use management. This study aimed to investigate the antibiotic resistance among hospital-acquired infections at Buu Dien General Hospital in Ho Chi Minh City in the period of 01-12/2017. Methods: This cross-sectional descriptive study was conducted on the retrospective data of all antibiograms of bacteria isolated from hospital-acquired infections at Buu Dien General Hospital in Ho Chi Minh City in the period of 01-12/2017 to investigate the antibiotic resistance. Characteristics of antibiotic resistance were described by frequency and percentage of types of bacteria isolated and antibiotics being resistant. Results: A total of 179 isolates were collected during the period 01-12/2017, of which E. coli was the most commonly isolated pathogen (41.3%). The highest prevalent infections were in the skin and mucosa; respiratory tract; and urinary tract (34.6%; 32.4%; and 27.9%). The antibiotic susceptibility testing used 21 types of antibiotics. Among them, S. aureus was 82% resistant to clindamycin and 75% resistant to cefuroxime; the Proteus resistance percentages to amoxicillin/clavulanic, second-generation cephalosporins, ciprofloxacin and fosfomycin varied from 50 to 93%; Pseudomonas was 92% resistant to fosfomycin and 62% resistant to ceftazidime; A. baumannii was resistant to most classes of agents used (50-75%). Both E. coli and Klebsiella were highly resistant to gentamicin, amoxicillin, ciprofloxacin, 2nd and 3rd generation cephalosporin’s. Polymyxin B-resistant Proteus cultures were detected at 67%. Conclusion: The study described the antibiotic resistance situation of hospital-acquired bacteria at the Buu Dien General Hospital from 01-12/2017. This information will aid physicians to select proper antibiotics for their patients in the next period.
Authors and Affiliations
Tran-Thi Ngoc-Van, Tran Quang-Thinh, Cu Thanh-Tuyen, Hoang-Thy Nhac-Vu
Keywords
Related Articles
- EP ID EP593442
- DOI 10.22159/ijpps.2019v11i7.32913
- Views 62
- Downloads 0
EFFECT OF CENTELLA ASIATICA (LINN) LEAVES ON SELECTIVE MITOCHONDRIAL AND CYTOSOLIC ENZYMES IN STREPTOZOTOCIN INDUCED DIABETIC RATS
Objective: The objective of the study is to evaluate the therapeutic effect of Centella asiatica leaves by assaying the activities of selective mitochondrial and cytosolic enzymes in the streptozotocin induced diabetic r...
FORMULATION AND PRODUCTION OF GRANULE FROM ANNONA MURICATA FRUIT JUICE AS ANTIHYPERTENSIVE INSTANT DRINK
Objective: The present study aims to formulate instant granule drink from soursop (Anonna muricata Linn) fruit juice and investigate its antihypertensive effect on Sprague-Dawley rats suffer from level 1 hypertensive dis...
FLAVONOID CONTENT AND ANTIBACTERIAL ACTIVITY OF ALBIZIA JULIBRISSIN. DURAZZ LEAF, STEM AND FLOWER EXTRACTS AGAINST CLINICALLY ISOLATED BACTERIAL PATHOGENS
Objective: Â To test the antibacterial efficacy of leaf, stem, and flower extracts of Albizia julibrissin against bacterial pathogens.Methods: Â Extraction of active metabolites was carried out by using six different sol...
A GLOBAL COMPARISON AND ANALYSIS OF NEURAMINIDASE H1N1 STRAIN OF INFLUENZA A
Objective: To evaluate the variation of neuraminidase (NA) protein from various H1N1 strain for drug designing.Methods: In this study we have used 12 sequences of NA protein from various countries, retrieved from Uniprot...
ASSESS THE PREVALENCE OF RESPIRATORY PROBLEM AND KNOWLEDGE ON HEALTH EFFECTS OF PEOPLE RESIDING NEAR QUARRY
Objective: In the quarry area, there are various suspended particulate matters are mixed with the ambient air in and around. People residing near to that quarry areas are exposed to hazards through the inhalation of airb...