Lacto-D3; The sunshine vitamin provides vitamin d3 optimum strength

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Lacto-D3; The sunshine vitamin provides vitamin d3 optimum strength

Journal Title: International Journal of Research in Pharmacology & Pharmacotherapeutics (IJRPP) - Year 2012, Vol 1, Issue 1

Abstract

Supplementation of cholecalciferol (vitaminD3 ) significantly reduces all-cause mortality emphasizes the medical, ethical, and legal implications of promptly diagnosing and adequately treating VitamnD3 deficiency. Not only are such deficiencies common, and probably the rule, VitamnD3 deficiency is implicated in most of the diseases of civilization. Vitamin D3’s final metabolic product is a potent, pleiotropic, repair and maintenance, seco-steroid hormone that targets more than 200 human genes in a wide variety of tissues, meaning it has as many mechanisms of action as genes it targets. One of the most important genes VitamnD3 up-regulates is for cathelicidin, a naturally occurring broad-spectrum antibiotic. Natural VitamnD3 levels, those found in humans living in a sun-rich environment, are between 40-70 ng/mL, levels obtained by few modern humans. Assessing serum 25-hydroxy- VitamnD3 (25(OH)D) is the only way to make the diagnosis and to assure treatment is adequate and safe. Three treatment modalities exist for VitaminD3 deficiency: sunlight, artificial ultraviolet B (UVB) radiation, and VitamnD3 supplementation. Treatment of vitamin D deficiency in otherwise healthy patients with 2,000-7,000 IU VitamnD3 per day should be sufficient to maintain year-round 25(OH)D levels between 40-70 ng/mL. In those with serious illnesses associated with VitamnD3 deficiency, such as cancer, heart disease, multiple sclerosis, diabetes, autism, and a host of other illnesses, doses should be sufficient to maintain year-round 25(OH)D levels between 55-70 ng/ mL. Vitamin D 3-deficient patients with serious illness should not only be supplemented more aggressively than the well, they should have more frequent monitoring of serum 25(OH) D and serum calcium. Vitamin D3 should always be adjuvant treatment in patients with serious illnesses and never replace standard treatment. Theoretically, pharmacological doses of VitamnD3 (2,000 IU/kg/day for three days) may produce enough of the naturally occurring antibiotic cathelicidin to cure common viral respiratory infections, such as influenza and the common cold, but such a theory awaits further science. The present paper Reviews the role of VitamnD3 in preventing different human disorders.

Authors and Affiliations

Govind shukla

Keywords

EP ID EP411695
DOI -
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