Level of Serum Lactate Dehydrogenase Enzyme in Oral Lichen Planus-A Biochemical Study
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 3
Abstract
Aims and Objectives: Evaluation of alteration in serum LDH in patients with erosive lichen planus and to compare it with that of controls. Materials and Methods: Blood samples were collected using standardized methods in subjects divided equally into two groups [control group and oral lichen planus group (n=20)].Biochemical assays for LDH was done. The serum levels of LDH in patients with erosive lichen planus was compared with that of the controls.Results: This study showed no significant difference in serum levels of LDH among Lichen planus and control group. (MD = 37.000, p-value = 0.427). Conclusion: Simce the histochemical study of oral mucosal tissue has demonstrated a marked difference between lactate dehydrogenase activity in oral lichen planus lesions as compared to normal and chronically inflamed oral mucosa; definite biochemical alterations may occur in serum also concurrently with the development of oral erosive lichen planus. But in order to establish this factor, multi centric trails including the follow-up of patients are necessary to understand the true value of serum LDH level as a prognostic parameter in oral lichen planus .
Authors and Affiliations
Arya S Nalin, Rajeev R, Giju Baby George, Sheeba Padiath
Keywords
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