LUTEAL PHASE SERUM CALCIUM AND SERUM MAGNESIUM LEVELS IN CAUSATION OF PREMENSTRUAL SYNDROME
Journal Title: International Journal of Basic and Applied Physiology - Year 2015, Vol 4, Issue 1
Abstract
Background: Premenstrual syndrome involves a variety of physical, mental and behavioural symptoms tied to a woman’s menstrual cycle. It is a complex health problem and is currently defined as the cyclical occurrence of non-specific somatic, psychological or behavioural symptoms linked to luteal and premenstrual phase of the menstrual cycle and are of sufficient severity to result in deterioration of interpersonal relationships, interference with normal activities or both. The severity of symptoms varies from person to person. The aim of the study is to investigate the relationship between levels of serum calcium and magnesium and symptom severity in patients with premenstrual syndrome. Method: For this we have taken 50 females of age group 15-45 years out of which 25 were controls and 25 had reported symptoms of PMS .Serum calcium and serum magnesium levels were estimated during pre and post-menstrual phases and normal subjects were compared with those having premenstrual syndrome. Serum calcium was measured by Ensure biotech O-cresol phthalein complexone (OCPC )method and serum magnesium by calmagite method. Result: This study showed a significant decrease in serum calcium (Chi-square value-4.93 and p-value - < 0.05 )and decrease in serum magnesium(Chi- square value-5.03 and p-value-<0.05) during premenstrual phase of PMS when compared with normal subjects. This study also suggested that PMS occurs in all age groups and is more prevalent in working women. Conclusion: This study led to a conclusion that there is a significant association between lowered serum calcium and serum magnesium levels during premenstrual phase with the severity of symptoms in PMS.
Authors and Affiliations
Garima Sharma, Pooja Tandon
Keywords
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