Malignant melanoma metastasis to pancreas diagnosed by endoscopic ultrasound guided fine needle aspiration Cytology: A case report
Journal Title: IP Archives of Cytology and Histopathology Research - Year 2017, Vol 2, Issue 1
Abstract
Pancreatic metastasis of malignant melanoma is rarely diagnosed on EUS FNAC while the patient is alive. Primary or secondary pancreatic malignant melanoma are rarely described in the literature. Most of the cases have been reported in the literature by surgical pathology. A 52-year-old male patient presented with 3 episodes of pain in abdomen for last 15 days. Patient had history of blackish discoloration with mass in big toe which was amputated 1 year age. On examination, multiple soft to firm non tender nodules palpable over right shin, right thigh and over right scapula. Patient was admitted for evaluation of pancreatic mass. CT abdomen and thorax showed lobulated heterogenous mass replacing pancreas with encasement of splenic vessels. Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) was performed from the mass of the pancreas. A probable cytomorphological diagnosis of malignant melanoma metastatic to pancreas was made. The final diagnosis of malignant melanoma was confirmed by strong positivity of HMB45 and S100 immunocytochemical staining on endoscopic ultrasound-guided fine needle aspiration cytology (EUS-FNAC). We report a very unusual case of malignant melanoma metastatic to pancreas diagnosed by EUS-FNAC. Although this is uncommon in the pancreas, malignant melanoma should be considered in the differential diagnosis of metastatic pancreatic masses on cytology.
Authors and Affiliations
Ram Nawal Rao, Paramita Paul, Sanjay Kannaujja, Praveer Rai
Keywords
Related Articles
- EP ID EP315998
- DOI -
- Views 93
- Downloads 0
Analysing false negatives and false positives in cytopathology of breast masses along with cytohistopathological correlation
Introduction Carcinoma of the breast is the leading cause of death in women due to malignancy Approximately 1000000 cases occur worldwide annually Evaluation of the breast masses is of utmost important for its timely man...
A study of papanicolaou stain and cervical acid phosphatase papanicolaou stain in the detection of cervical intra epithelial neoplasm a comparative study
Introduction In order to increase the sensitivity of the routine PAP test a new test was introduced called the CAPPAP test In this test lysosomal enzyme and cervical acid phosphatase CAP enzyme are labeled with conventio...
Endometrial histopathology in abnormal uterine bleeding
Introduction: In routine practice abnormal uterine bleeding (AUB) is a distinct entity. In women of reproductive age with episodic unpredictable bleeding it is an indication of number of pathologic disorder. Histopatholo...
Stepping on diagnosis with step sections- An institutional experience
Introduction A thorough morphological assessment plays a central role in evaluation of skin biopsies Overlapping microscopic features pose additional diagnostic challenges in dermatopathological practice More over skin b...
Cytomorphology of breast lesions with historadiological correlation in a tertiary care centre of Puducherry
Introduction Breast cancer is the leading cause of morbidity amp mortality worldwide Breast being a surface organ is easily palpable for aspiration Diagnosis is often done by correlating fineneedle aspiration cytology FN...