Management of diabetic foot ulcers with platelet rich plasma: A clinical study
Journal Title: National Journal of Clinical Orthopaedics - Year 2018, Vol 2, Issue 3
Abstract
Background: Diabetic foot is a frequent site for complication in DM. Ulceration occurs as a result of trauma in the presence of neuropathy and/or peripheral vascular disease with infection as a secondary phenomenon following disruption of the protective epidermis. The present study was conducted to determine the role of autologous platelet rich plasma in healing of diabetic foot ulcers. Materials & Methods: The present study was conducted on 20 cases of diabetic foot ulcers. In all patients, ulcer size as per maximum length and breadth and area were recorded and two PRP dressings were given on day 0 and second after first week. The size was measured in maximum length and maximum breadth by using a scale and area was calculated. Results: Out of 20 patients, males were 10 and females were 10. The difference was non- significant (P-1). Age group 30-50 years had 2 males and 1 females, 50-70 years had 3 males and 5 females and >70 years had 5 males and 4 females. The difference was significant (P-0.05). there was <60% reduction in 1 male, 61-70% reduction in 1 male and 1 female, 71-80% reduction in 2 males and 4 females and >80% reduction in 6 males and 5 females. The difference was significant (P<0.05). Conclusion: PRP seem to be an effective and safe preparation used for therapy of DFU. PRP is an autologous product, therefore constitutes no risk of viral hepatitis or HIV infection.
Authors and Affiliations
Vinay Kumar Tripathi, Dr. Parijat gupta
Keywords
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