Management of Hepatitis C Infection with Direct Action Antiviral Drugs (DAA)**
Journal Title: Archives of Hepatitis Research - Year 2015, Vol 1, Issue 1
Abstract
Several new direct action antiviral drugs (DAA) against the HCV virus (HCV) are approved and marketed. The combination of DAA with pegylated interferon and ribavirin (PR) is only recommended to patients with tolerance to interferon (IFN). IFN-free treatments are now considered elective drugs for patients with chronic HCV. More than 90% of patients infected with HCV genotype 1 or 4 (fewer with other genotypes) show sustained virological response, when treated with sofosbuvir combined with simeprevir, daclatasvir or ledipasvir, or by the combination of paritaprevir with ritonavir, ombitasvir and dasabuvir, with or without ribavirin.
Authors and Affiliations
Focaccia Roberto, de Mello Rodolfo Ferreira, Montes Patrícia Silva, Conti Flávio Martin
Keywords
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- EP ID EP558574
- DOI 10.17352/ahr.000003
- Views 49
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