Maternal and fetal outcome in pregnancy specific liver disorders
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 4
Abstract
Background and aim – Normally some hepatic changes occurs in pregnancy, but they needed to be differentiated from pathologies which carry significant risk to the mother and fetus. Liver dysfunction during pregnancy is multifactorial in origin and diagnosis is often challenging. So, we did this study to know the effect of pregnancy specific liver disorder on the maternal and fetal outcome. Methods - This was a hospital-based prospective observational study done over a period of 12 months from January 2017 to December 2017. All pregnant women booked or unbooked, who presented with pregnancy related liver dysfunction to our antenatal clinic or admitted in the obstetrics ward based on clinical and laboratory parameters were included for the study. Results - Incidence of pregnancy specific liver disorder was 0.89%. Preeclampsia (74) was the common cause of liver dysfunction in pregnancy followed by ICP (46) and HELLP syndrome (22). There were 2 spontaneous abortions. 25.5% patients delivered vaginally and 74.5% underwent the cesarean section. The most common maternal complication was DIC (9.39%). There were 5 maternal deaths. Among the 152 births (3 twin pregnancies), 131 were live births, 89 had low birth weight. There were 8 intrauterine deaths, 13 stillbirths, and 11 neonatal deaths. Perinatal mortality was 21.05%. Conclusion - Pregnancy with liver disorder results in very high fetal as well as maternal morbidity and mortality.
Authors and Affiliations
Dr. Suryawanshi Shatabdi
Keywords
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