MEDICATION ADHERENCE IN OUTPATIENTS WITH ARTERIAL HYPERTENSION
Journal Title: Acta Facultatis Medicae Naissensis - Year 2013, Vol 30, Issue 0
Abstract
The degree of patient cooperation plays a key role in the success of antihypertensive drug therapy. Non-adherence is the major health and economic problem in the treatment of arterial hypertension (HTA). The aim of the study was to evaluate the degree of adherence in hypertensive patients and to study risk factors affecting adherence and the effects of non-adherence on blood pressure (BP). We performed a cross-sectional study, which involved 170 outpatients with HTA, treated in primary healthcare. Patients were divided into two groups, depending on the degree of adherence, measured using a validated survey form. Statistical analysis was performed using the Pearson's Chi-square and t-test. Good adherence was observed in 126 (74.12%) outpatients. Elderly patients with longer duration of HTA and larger number of drugs in the therapy showed a lower degree of adherence, with more side-effects (p<0.01). Patients younger than 65 years were found to be more likely to adhere to their medication regimen, compared to elderly patients (2=21.3; p<0.01; OR=6.0 95%, CI 2.76-13.04). Uncontrolled BP occurred in the significantly higher percentage in non-adherent patients (59.1%) compared to the adherent group (21.4%) (2=19.84; p<0.01; OR=5.30 95%, CI 2.39-11.85). The most common reason for poor adherence was non-compliance with dosage regimen (27.27%). The medication adherence rate was found to be low among elderly patients. A poor adherence was found to negatively affect BP control. Determining the factors for non-adherence and developing multidisciplinary intervention programs to address the identified factors are necessary to improve adherence to medication and BP control.
Authors and Affiliations
Jelena Lalić, Radmila Veličković Radovanović, Branka Mitić, Valentina Nikolić, Ana Spasić, Goran Koraćević
Keywords
Related Articles
- EP ID EP141792
- DOI 10.2478/afmnai-2013-0013
- Views 97
- Downloads 0
DIJAGNOZA I KLINIČKI ZNAČAJ HUMANE DIROFILARIOZE
Vrste Dirofilaria repens (D. repens) i Dirofilaria immitis (D. immitis) paraziti pasa, dugo poznati uzročnici zoonoza, mogu kao nezrele jedinke da parazitiraju i u organizmu čoveka. Humana dirofilarioza kod mnogih asimpt...
The Association between Helicobacter Pylori Infection in Subjects with Gastritis and Serum Levels of LL-37, MBL and M-Ficolin
Helicobacter pylori (H. pylori) can stimulate immune responses and lead to the release of proinflammatory factors and antimicrobial peptides as LL-37, mannose-binding lectin (MBL) and M –ficolin. The aim of this study wa...
TELECONSULTATION IN DENTISTRY USING THE XPA3 ONLINE SYSTEM: CASE REPORT
Telemedicine represents interactive audio-visual communication between doctors and their patients. The Center for Telemedicine in Kosovska Mitrovica organizes and manages the process of teleconsultation using the compute...
Comparison of the Effects of Artemisia Vaginal Cream and Clotrimazole on Vaginal Candidiasis Infection
Candida vaginitis is the second most common vaginal infection which is treatable by azole. Over-consumption of azole is associated with resistance to drug and treatment failure. Studies conducted in laboratory conditions...
HEREDITARY HAMARTOMATOUS GASTROINTESTINAL POLYPOSIS SYNDROME
Hamartomas represent localized overgrowth of cells in the parts which are normally associated with polyps, ie. mesenhimal, stromal, endodermal and ectodermal elements. Hamartomatous polyposis syndromes carry a significan...