Medullary Aplasia in the Child: Epidemiological, Clinical and Biological Aspects in the Hematology Laboratory of CHU Hassan II of Fez
Journal Title: Saudi Journal of Pathology and Microbiology - Year 2017, Vol 2, Issue 4
Abstract
Abstract: Medullary aplasia (MA) is a rare and severe affection. It is much rarer in children. The etiologies are multiple: constitutional, acquired, and idiopathic. In order to evaluate the epidemiological, clinical and biological aspects of bone marrow aplasia in a pediatric population, we carried out a retrospective study of 9 cases collected in the hematology department in collaboration with the department of anatomy pathology of the Hassan II CHU in Fez over a four-year period from January 2013 to December 2016. Age ranged between 1 and 14 years, with a sex ratio of 3.5. The anemic, hemorrhagic and infectious syndrome was noted respectively in: 9, 7, and 6 cases. The hemoglobin varied between 3.3 and 7.3 g/dl with an average of 5 g/dl, anemia is normochrome normocytic argenerative in all our patients. Neutropenia was found in 100% of patients, and all patients had thrombocytopenia with platelet counts ranging from 500 to 105000/mm3. The BOM-coupled myelogram was performed in all patients, confirming the diagnosis of AM. For the etiologies, Fanconi Anemia was evoked in 4 cases and idiopathic in 5 patients. Keywords:Medullary aplasia in the child, epidemiology, biology, laboratory CHU Hasssan II Fez.
Authors and Affiliations
Amadou Djibrilla, Pr. Imane Tlamcani, Imane Jamai, Boubacar S. Marou, Nazik El. Hammouni, Moncef Amrani, Boubacar Efared, Hinde El Fatemi
Keywords
Related Articles
- EP ID EP386279
- DOI -
- Views 49
- Downloads 0
A Comparative Study of Conventional and Automated Culture System [BACTEC] For Detection of Bacterial Infection
Isolation of microorganisms is very important for accurate treatment and is one of the important concerns for clinical microbiologists. The accuracy and rapidity of treatment are critical for successful treatment. The pr...
Primary Actinomycosis in Male Breast Mimicking Malignancy – A Rare Case Report with Review of Literature
Primary actinomycotic infection is a rare finding in breast with very few cases been reported in male breast and it is seen to be associated with trauma to skin or any predisposing conditions like diabetes mellitus. We a...
Vancomycin Resistance in Clinical Isolates of Methicillin Resistant Staphylococcus aureus from a Tertiary Care Hospital
Staphylococcus aureus is one of the most common causes of Blood Stream infections (BSI), skin and wound infections, osteomyelitis, endocarditis, and nosocomial infections, especially pneumonia, surgical site infections (...
HemosideroticFibrolipomatous Tumor or Pleomorphic HyalinizingAngiectatic Tumor of Soft Parts?: Cytology and Histology of an Unusual Tumor
Abstract:HemosideroticFibrolipomatous Tumor (HFLT) and pleomorphic hyalinizingangiectatic tumor of soft parts (PHAT) are rare, locally aggressive neoplasms with overlapping morphological and immunohistochemical features....
An adult onset Still’s disease in a young man within waves of dengue fever syndromes
Abstract:We describe the first case report of an Adult Onset Still’s Disease (AOSD) in a previously healthy young man from Jazan, Saudi Arabia in the summer of 2017. The patient symptoms, signs and investigations fulfill...