Method development and validation of Pioglitazone and Saxagliptin by RPHPLC

Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2017, Vol 5, Issue 1

Abstract

Analytical method by using RP-HPLC was developed for the determination of saxagliptin and pioglitazone. Potassium dihydrogen phosphate buffer : methanol (80:20 v/v) was used as mobile phase. The detection wavelength was 272 nm, flow rate of 1ml/min and retention time of Saxagliptin was 2.998 minutes and Pioglitazone was 4.310 minutes. The method was validated and all the parameters were within the limits.

Authors and Affiliations

Bolagani Sarada, K Narendra Kumar Reddy, Bada Pragati Kumar

Keywords

Related Articles

A Study of Serious Adverse Event associated with the use of Antiproliferative Immunosuppressive Drugs (MMF) in organ transplanted Patients

Organ transplantation by Mycophenolate mofetil (MMF) is crucial component for treatment of choice for patients suffering from End Stage of Organ Disease, But to prevent the patient life, after transplantation the forem...

Design and Evaluation of Bilayered Tablets of Amlodipine Besilate with Enalapril Maleate

Bilayer tablets of Amlodipine Besilate (Immediate Release) Enalapril Maleate (Sustained Release) were formulated for treatment of hypertension. The main objective of this combination is to encourage the low doses of dr...

Assessment of RO water plants in warangal district

Reverse Osmosis (RO) process is currently using best technique to purifying the water. The chemist has vital role in RO Plants. The present study clearly gives the best idea about how the RO plants are running in the W...

A COMPREHENSIVE REVIEW OF ELADI VATI

Herbal medicines are the synthesis of therapeutic experiences of generations of practising physicians of indigenous systems of medicine for over hundreds of years while nutraceuticals are nutritionally or medicinally e...

FORMULATION AND EVALUATION OF ORAL CONTROLLED FLOATING TABLETS OF ANTI-ASTHAMATIC DRUG

The objective of the present research work is to formulate and evaluate oral controlled floating tablet of anti-asthmatic drug Terbutaline sulphate. The pre and post compression parameters have been studied and the res...

Download PDF file
  • EP ID EP33429
  • DOI -
  • Views 324
  • Downloads 0

How To Cite

Bolagani Sarada, K Narendra Kumar Reddy, Bada Pragati Kumar (2017). Method development and validation of Pioglitazone and Saxagliptin by RPHPLC. Indian Journal of Research in Pharmacy and Biotechnology, 5(1), -. https://europub.co.uk/articles/-A-33429