Microencapsulation: A vital technique in novel drug delivery system
Journal Title: Journal of Pharmaceutical Sciences and Research - Year 2009, Vol 1, Issue 4
Abstract
Novel drug delivery systems have several advantages over conventional multi dose therapy. Much research effort in developing novel drug delivery system has been focused on controlled release and sustained releasedosage forms. Now considerable efforts are being made to deliver the drug in such a manner so as to get optimum benefits. There are various approaches in delivering a therapeutic substance to the target site in asustained controlled release fashion. One such approach is using microspheres as carriers for drugs. Microencapsulation is a process where by small discrete solid particles or small liquid droplets are surroundedand enclosed by an intact shell. Microencapsulation is used to modify and delayed drug release form pharmaceutical dosage forms. A well designed controlled drug delivery system can overcome some of the problems of conventional therapy and enhance the therapeutic efficacy of a particular drug. It is the reliable means to deliver the drug to the target site with specificity, if modified, and to maintain the desired concentrationat the site of interest without untoward effects. Microspheres received much attention not only for prolonged release, but also for targeting of anticancer drugs to the tumor. The intent of the paper is to highlight the potential of microencapsulation technique as a vital technique in novel drug delivery
Authors and Affiliations
Venkatesan P. , Manavalan R. , Valliappan K.
Keywords
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