MICROENCAPSULATION TECHNOLOGY
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2013, Vol 1, Issue 3
Abstract
Microparticulate drug delivery systems provide tremendous opportunities for designing new controlled and delayed release oral formulations, thus extending the frontier of future pharmaceutical development. The Microparticulate offers a variety of opportunities such as protection and masking, reduced dissolution rate, facilitation of handling, and spatial targeting of the active ingredient. It is the process by which individual particles or droplets of solid or liquid material (the core) are surrounded or coated with a continuous film of polymeric material (the shell) to produce capsules in the micrometer to millimeter range, known as microcapsules. Microencapsulation technology can protect active materials against environment, stabilize them, prevent or suppress volatilization. Microencapsulation technology can provide new forms and features and many polymeric drug delivery systems, biodegradable polymers have been used widely as drug delivery systems because of their biocompatibility and biodegradability. Microencapsulation is a powerful technique to achieve targeted delivery and on-demand release of different active ingredients. Many synthetic and natural biodegradable polymers present exciting opportunities in tailor-making the micro particle formulations for long-term drug release with specific release rates. Hence finally concluded that continuous knowledge up gradation is required in order to make desired drug delivery system and minimization of problems associated with physicomechanical techniques and complete knowledge about selection of raw materials and method for their microencapsulation to get desire goal of study.
Authors and Affiliations
K. P. Sampath KumarTejbe. Sk Shameem Banu P. Naga Lakshmi D. Bhowmik
Keywords
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