Miller Fisher Syndrome Presenting with Idiopathic Central Serous Chorioretinopathy: A Rare Association
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 6
Abstract
Introduction: Miller Fisher syndrome is a rare autoimmune disorder characterized with acute onset of diplopia, bilateral complete ophthalmoplegia, ataxia and areflexia. It is a variant of Guillian Barre Syndrome and carries a risk of progression to GBS in rare instances. But unlike GBS, MFS is a selflimiting condition with annual incidence of 0.09/100,000 populations, and because of its similarity with GB syndrome, prompt diagnosis and follow-up is required. Typical MFS has never been reported previously with Idiopathic Central Serous chorioretinopathy [ICSC]. Case report: 40 years old male presented with sudden onset diminution of vision, diplopia and associated neurological features suggestive of MFS. B.P. at the time of presentation was 150/100mm of Hg with no prior history of hypertension. On further evaluation patient was diagnosed with ICSC right eye along with MFS. Patient was managed with supportive treatment and systemic steroid was avoided. Patient recovered completely by 4th week. Conclusion: MFS is autoimmune neurological condition presenting as GBS. Because of its rarity, good clinical knowledge of this condition is essential for prompt diagnosis and management. MFS patients only require supportive treatment till complete neurological recovery. But rare severe cases may require immunosuppressive treatment. Association of ICSC with autoimmune conditions like Systemic Lupus Erythematous(SLE), Anti-phospholipid Ab syndrome is well known but association with MFS has never been reported earlier. In present case, association of ICSC with MFS and its resolution with resolution of systemic disease suggest some common pathophysiology, which needs further study.
Authors and Affiliations
Harsh Vardhan Singh, Shubhra Das
Keywords
Related Articles
- EP ID EP431402
- DOI -
- Views 122
- Downloads 0
Solitary Infantile Myofibromatosis at Distal end of Humerus: A Rare Case Report
Introduction: Infantile myofibromatosis is a rare benign disorder of mesenchymal origin presenting as tumors in skin, muscles,bones and soft tissue of head and neck. Its solitary occurrence in bones is very rare. It is e...
Role of Platelet Rich Fibrin in Healing of Extraction Socket
Introduction: Platelet Rich Fibrin (PRF) consists of an autologous leukocyte-platelet-rich fibrin matrix composed of a tetra molecular structure, with cytokines, platelets, cytokines, and stem cells within it which acts...
Incontinentia Pigmenti - Dental Manifestations: A Report of Two Cases
Introduction: Incontinentia Pigmenti or Bloch-Sulzberger syndrome is a rare form of ectodermal dysplasia, affecting the skin, hair, eyes, central nervous system and the teeth. This variant of genodermatosis is most preva...
Epidural Blood Patch For Postdural Puncture Headache - A Prospective Study of 60 Patients
Introduction: Spinal anaesthesia is used widely now a days. This dural puncture is associated with CSF leak which decreases the intracranial pressure and causes headache. The incidence of postdural puncture headache was...
Clinico-Radiographic Evaluation of Chronic Obstructive Pulmonary Disease Patients - A Hospital based Study
Introduction: COPD is a disease associated with prolonged duration of exposure to smoke and noxious particles. Hence, present study was undertaken to study clinico-radiographic profile of chronic obstructive pulmonary di...