МОЛЕКУЛЯРНО-ГЕНЕТИЧНИЙ МЕТОД ДІАГНОСТИКИ ПАРОДОНТИТУ
Journal Title: World Science - Year 2017, Vol 5, Issue 6
Abstract
Illnesses of parodontitis occupy one of major places among problems in modern dentistry. Considerable prevalence, severe loss of teeth for patients, unfavorable influence of hearths of parodontitis infection on an organism is determined actuality of problem of complex diagnostics and treatment of this pathology. A research aim is an estimation of features of composition of parodontitis microbiota in content folds of gums by means of polymerase chan reaction of differential diagnostics at chronic simple and complicated parodontitis. Materials and research methods. We are conduct an inspection 67 persons in age from 60 to 20, that suffer on the different forms of parodontitis. A control (К) group was laid down by 16 persons that did not have external signs of parodontitis. The complex of clinical methods was standard (questioning, research, sounding, estimation of degree of mobility of teeth, estimation of the state of tissues of parodontitis. Research results. For all patients with the set diagnosis the chronic periodontitis of research polymerase chan reaction allowed to distinguish in content of the parodontitis pocket of DNA all parodontitispathogenic kinds in the considerable percent of cases : for 42 persons (of 66,7%) - P. gingivalis, in 39 (61,9%) - B. forsythus, in 38 (60,3%) - T. denticola, in 34 (53,9%) - P. intermedia, in 29 (46,0%) - A. actinomycetemcomitans. Conclusions. Analysing intercommunication of clinical parameters and presence of microbiota of gingival pockets, we educed dependence between the increase of frequency of exposure of paradontopathogenic and expressiveness of clinical displays. Especially evidently intercommunication is traced between patients with the easy and middle degree of weight. There is correlation between the increase of frequency of exposure of paradontopathogenic in the gingival pockets of area and expressiveness of clinical displays.
Authors and Affiliations
І. В. Янішен, Г. Г. Гришанін, І. Л. Дюдіна, І. О. Перешивайлова, А. В. Погоріла
Keywords
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