Multidrug Resistant Acinetobacter Infection in Surgical Intensive Care Unit in a Tertiary Care Center in North India
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 3
Abstract
Introduction: Acinetobacter is nowadays a common threat in hospital, acquired especially in critically ill patients admitted to intensive care unit. This study was done to determine the presence of MDR Acinetobacter species in patients admitted in surgical intensive care unit in our hospital, so that timely steps are taken to prevent their spread, protect patients from inappropriate therapy and ensure proper infection control measures. Material and Methods: Prospective study was designed in the Department of Microbiology and surgical intensive care unit, Sher I Kashmir Institue of Medical Sciences,Soura J&K, between December 2015 to March 2016. The samples were inoculated on 5% sheep blood agar and MacConkey agar and incubated overnight aerobically at 37ο C. After the isolation of typical colonies, the identification was done as per standard microbiological techniques. Antibiotic susceptibility was performed according to CLSI recommendations. Results: A total of 77 non duplicate samples were received from surgical ICU. Out of these 77 samples, 48 were positive and 29 samples were sterile. Out of 48 positive samples, 30 isolates of Acinetobacter spp were isolated. Maximum 23.3% were from the 60-70 year age group and maximum were obtained from tracheal aspirate 96.6%. Twenty five patients had prolonged hospital stay i.e; ≥ 7 days where as only 5 of the patients were in the hospital for ≤ 7 days before the Acinetobacter was isolated from their samples. Twenty eight were on ventilator support. Twenty nine (96.6%) isolates were resistant to Amikacin, and Tobramycin each. Higher resistance was also seen for Tetracycline, Tigecycline, Gentamicin, Levofloxacin and Cefotaxime (93.3% each). Twenty seven (90%) of isolates were resistant to Cefepime, 86.6% of isolates were resistant to Meropenem and Imipenem each. All the Acinetobacter isolated (100%) were sensitive to Polymyxin B. Nineteen isolates (63.3%) were sensitive to Pipercillin+tazobactum. Conclusion: Risk factors in ICU patients like advanced age, ventilator support, prolonged hospital stay should raise suspicion of MDR Acinetobacter infection and the antibiotic should be given only after susceptibility test.
Authors and Affiliations
Shugufta Roohi, Lubna Samad, Saba Wani, Bashir A Fomda, Mohd Suhail Lone, Junaid Ahmad, Akeela Fatima, Abiroo Jan
Keywords
Related Articles
- EP ID EP426820
- DOI -
- Views 87
- Downloads 0
A Study of Sociodemographic and Morbidity Profile of Women Residing in the Rural Area of Beed District
Introduction: In rural India adequate attention has not been focused at studying disease pattern, trend and its consequences along with the epidemiological transition. Also the health of the women is mostly neglected in...
Mucocutaneous Enigma – A Case Report (Multidisciplinary Management for Successful Treatment Outcomes)
Introduction: Lichen planus is a complex, mucocutaneous, chronic inflammatory disease of unknown etiology. The association of lichen planus with autoimmune disease has been found with equatorial racial and cosmopolitian...
A Study on Nodal Positivity in Central Compartment of Neck in Differentiated Thyroid Malignancies: A Study From Tertiary Care Center
Introduction: Thyroid malignancies are the difficult one to treat. The present study was designed to study the incidence of occult nodal metastases, total nodal yield and percentage of nodal positivity in central compart...
Is Microscopic Assessment of Macroscopically Normal Uterovaginal Prolapse Hysterectomy Specimens Necessary? - A Study In Konaseema Region
Introduction: Hysterectomy for symptomatic genital prolapse accounts for about 15% of hysterectomies performed. The study is to know whether the histopathological examination of the hysterectomy specimens is really neces...
Intrathecal Nalbuphine an Effective Adjuvant for Post Operative Analgesia (A Comparitive Study with Fentanil)
Introduction: Various adjuvants have been used along with local anaesthetics for prolongation of analgesia post operatively in neuraxial blockade. The frequently used adjuvants are opioids, midazolam, neostigmine, ketami...