Multiple Myeloma Presenting as Spinal Cord Compression: A Report of Five Cases
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 4
Abstract
Introduction: Multiple Myeloma is a hematologic malignancy of plasma cells resulting in lytic bone lesions, M-protein in serum and renal insufficiency. Multiple Myeloma accounts for 1% of all malignancies and 10-20% of all haematological malignancies. Patients of Multiple Myeloma mostly present with pain, tenderness and pathological fractures. Multiple Myeloma causing skeleton related events are not uncommon. Among them, spine is one of the most commonly involved. Myeloma lesions may extends through the cortex of a vertebral body resulting in spinal cord compression. Case report: Here we are reporting FIVE cases, who presented initially with spinal cord compression. The patients were subjected to MRI scan and biopsy of the collapsed vertebrae was taken. The histopathological and the hematological reports confirmed a diagnosis of Multiple Myeloma. Conclusion: Spinal cord compression is an uncommon complication of Multiple Myeloma. A diagnosis of Multiple Myeloma should be thought of in cases of spinal cord compression. Usually this complication is associated with far advanced malignancy and a poor prognosis.
Authors and Affiliations
Mondita Borgohain, Pranjal Kumar Gogoi, Sujay Karmakar, Pradeep K
Keywords
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