Mutual Homeostatic Regulation Between Natriuretic Peptides And Mineralocorticoids In The Cardiovascular System
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2018, Vol 13, Issue 5
Abstract
The two natriuretic peptides, A-type Natriuretic peptide (ANP), B type Natriuretic peptide (BNP) are released by the heart while C-type natriuretic peptide (CNP) is mostly expressed in the brain but also by the endothelial cells and heart and they induce natriuresis and have vasodilatory actions. On the other hand, aldosterone released by the adrenal cortex may regulate the release of natriuretic peptides by acting on specific receptors in the heart and increasing the circulating sodium and ECF levels. This article examines the mutually homeostatic regulatory role of natriuretic peptides and aldosterone in maintaining cardiovascular system and other possible biological roles. This may be more relevant in cardiovascular disorders like hypertension and cardiac failure.
Authors and Affiliations
Manoj G Tyagi, Farkhanda Naila Syed, Mahendra Kumar Verma
Design and Synthesis of novel Chalcone Derivatives and their Antioxidant Activit
A simple and effective synthesis of pyrazoles and cyanopyridines derivatives from Chalcone according to Claisen-Schmidt condensation. Chalcone, (2E)-N-(4-((2,6-bis(4-methoxyphenyl)-3- methylpiperidin-4-ylidene)amino)phen...
Multiplex PCR identification of eight clinically relevant Candida species isolated from groin Fungal Infections among Egyptian patients
The prevalence of fungal infections has raised in recent years due to an increasing population of immunosuppressed patients, intensive immunosuppressive chemotherapy, increasing awareness of fungal infections, and the wi...
Development and Validation of an Inductively Coupled Plasma Mass Spectrometry (ICP-MS) Method for the Determination of 17 Trace Metals in Ingenol Mebutate (API)
In this study elemental impurities method of quantitative analysis for the determination of trace metals in Ingenol mebutate (API) by ICP-MS was validated and applied. ICP-MS is a multi-element technique characterized by...
Potential Use of Rosemary (Rosmarinus officinalis L.) Essential Oil as Anti-Bacterial and Anti -Algal
The activity of Rosmarinus officinalis (Rosemary) essential oil screened for multi medicinal or pharmaceutical and industrial purposes as an alternative for chemical solutions with long-term and devastating side effects....
Detection of The Optimum Conditions For The Amplification of Some Regions In The Multidrug Resistance Gene In Acute Myeloid Leukemia Patients In Iraq
A molecular study on MDR1 gene by a specific PCR is carried out for the patients of acute myelogenous leukemia before and after chemotherapy to study the possible alteration in MDR1 gene and its correlation with developm...