Mutual Homeostatic Regulation Between Natriuretic Peptides And Mineralocorticoids In The Cardiovascular System
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2018, Vol 13, Issue 5
Abstract
The two natriuretic peptides, A-type Natriuretic peptide (ANP), B type Natriuretic peptide (BNP) are released by the heart while C-type natriuretic peptide (CNP) is mostly expressed in the brain but also by the endothelial cells and heart and they induce natriuresis and have vasodilatory actions. On the other hand, aldosterone released by the adrenal cortex may regulate the release of natriuretic peptides by acting on specific receptors in the heart and increasing the circulating sodium and ECF levels. This article examines the mutually homeostatic regulatory role of natriuretic peptides and aldosterone in maintaining cardiovascular system and other possible biological roles. This may be more relevant in cardiovascular disorders like hypertension and cardiac failure.
Authors and Affiliations
Manoj G Tyagi, Farkhanda Naila Syed, Mahendra Kumar Verma
Keywords
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- EP ID EP415710
- DOI 10.9790/3008-1306010104.
- Views 85
- Downloads 0
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