N-alkylation methods, Characterization and Evaluation of antibacterial activity of some Novel 5-Chloroisatin Derivatives
Journal Title: International Journal of engineering Research and Applications - Year 2017, Vol 7, Issue 6
Abstract
A series of new 5-Chloroisatin derivates have been synthesized by the method of N-alkylation at room temperature, in the presence of a base and a catalyst with good yields. The chemical structures of these compounds were confirmed by NMR (1H &13C), these new compounds obtained were evaluated for their antibacterial activity. The final results revealed that the majority of the compounds exhibited good antimicrobial activity against various organisms.
Authors and Affiliations
Z. Tribak, O. El Amin, M. K. Skalli, O. Senhaji, Y. Kandri. Rodi, M. Houssaini. Iraqui
Keywords
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