Na+/Ca2+ EXCHANGER AS A TARGET FOR STATIC MAGNETIC FIELD
Journal Title: World Science - Year 2018, Vol 3, Issue 5
Abstract
The presented work attempted to study the effects of SMF-treated RS and SMF-treated K+-free RS on hibernating snail, when the Na+/K+ pump was in passive and artificially blocked states, respectively. The Ca2+ uptake, cell hydration level and membrane potential of Helix pomatia snail neurons were investigated. Results have shown, that SMF-treated RS elevated Ca2+ uptake in hibernating snail leading to the synaptic activation of the snail neuron. SMF-treated K+-free RS does not significantly change the amount of absorbed Ca2+ ions, however it leads to the decrease of hydration level of the ganglia as compared to the experiments performed with the untreated K+-free RS. This is accompanied by the inhibitory effect on cell electrical activity. According to the obtained results it can be concluded that (1) The SMF-treated RS effect on hibernating snail ganglia neurons is realized via activation of R Na+/Ca2+ exchanger, and (2) the SMF-induced effect is not implemented by the Na+/K+ pump because in case of applying K+-free RS the SMF effect is still observed, but the manifestation of its effect strongly depends on the functional state of the pump.
Authors and Affiliations
Naira Baghdasaryan, Gohar Musheghyan, Zhenik Chobanyan, Sinerik Ayrapetyan
Keywords
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- EP ID EP294363
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