Natural Products: An Important Source for the Treatment of Psychosis
Journal Title: Archives of Organic and Inorganic Chemical Sciences - Year 2018, Vol 3, Issue 3
Abstract
Psychosis is a mental disorders or psychiatric disorders due abnormal condition of the mind that results in difficulties telling what is real and what is not [1]. It is a wide range of condition that affects mood, behaviour and thinking. Psychosis is characterized by hallucination in vision, hearing, smelling and tasting etc. The person suffered from psychiatric disorders may include symptoms of false beliefs and seeing or hearing things that others do not see or hear [1]. Other symptoms may include disorganized thinking, incoherent speech and behaviour that are inappropriate for the situation [2]. There may also be, sleep problems, loss of motivation and social withdrawal, and difficulties carrying out daily activities [2]. The person experiencing psychosis may also have thoughts that are contrary to actual evidence; these thoughts are known as delusions. Psychosis is associated with several medical disorders and conditions like schizophrenia, schizophreniform disorder, and schizoaffective disorder: delusional disorder, substance-induced psychosis, dementia and bipolar disorder (manic depression) [2,3].Psychosis is one of the most dreaded disease of the 20th century and spreading further with continuance and increasing incidences in 21st century. In 2004, the World Health Organisation estimated that over 26 million people suffered from schizophrenia, making it one of the top 20 causes of disability worldwide.3 Furthermore, in 2004, 30,000 deaths were attributed to the condition.3 According to the 2013 Global Burden of Disease study, the predominant mental health problem worldwide is depression, followed by anxiety, schizophrenia and bipolar disorder. Globally, more than 300 million people suffer from depression, and 260 million suffer from anxiety disorders many of whom live with both conditions. A study by the World Health Organization found that such disorders cost the global economy $1 trillion in lost productivity each year [4,5]. The treatment of psychosis depends on the specific diagnosis (such as schizophrenia, bipolar disorder or substance intoxication). The first-line treatment for many psychotic disorders is antipsychotic medication. Antipsychotics, also known as neuroleptics or major tranquilizers. They are also associated with increased mortality in elderly people with dementia. There are two types of Antipsychotic drugs First-generation antipsychotics, known as typical antipsychotics, were discovered in the 1950s. Most secondgeneration drugs, known as atypical antipsychotic drugs. The longterm use of antipsychotics is associated with side effects such as involuntary movement disorders, gynecomastia, and metabolic syndrome [2,4,5].
Authors and Affiliations
Shweta Kushwaha, Anupam Maurya
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