CORRELATION BETWEEN HIGH SENSITIVITY C-REACTIVE PROTEIN AND LIPIDS IN OBESITY AMONG INDIANS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2015, Vol 4, Issue 42
Abstract
[b] BACKGROUND[/b]: Obesity has increased in prevalence to an epidemic proportion. The causes of which are many. There is also increase in the incidence of cardiovascular events in parallel with it. Central obesity (Visceral adipocity) is a key regulator of inflammation. Dyslipidemia is major risk factor for ischemic heart disease. Atherosclerosis, an inflammatory condition is a precursor for cardiovascular disease. High sensitivity C reactive protein, a major marker of systemic inflammation is increased in Ischemic heart disease as evidenced by various studies. In this study we looked at correlation between high sensitivity C-reactive protein and lipid parameters. [b]OBJECTIVE:[/b] To correlate between high sensitivity C- reactive protein (hsCRP) and lipid profile in obese and nonobese Indians. [b]MATERIALS AND METHODS:[/b] Eighty-eight participants were enrolled for the study after inclusion and exclusion criteria were met. History and physical examination was done including blood pressure. BMI was calculated and below 23kg/m2 was considered normal. Routine blood investigations were done. HDL, LDL, Triglycerides, total Cholesterol and hsCRP were measured using standardized methods. Participants with BMI of <23 kg/m2 were categorized as cases and those with BMI>23kg/m2 as cases. [b]RESULTS[/b]: Out of 88 participants 34 were female and 54 were men. Twentysix females and 39 men were obese among the participants. Obese females with low HDL and all obese participants had higher statistically significant mean CRP of 5.94±2.97mg/L and 4.78±2.59 mg/L respectively. All other parameters had insignificant correlation. [b]CONCLUSION[/b]: HsCRP correlates with triglycerides in obese individuals. HsCRP correlates with obesity.
Authors and Affiliations
Sadanand C. D, Bindumathi P. L. , Madhusudhana L.
Keywords
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- EP ID EP122741
- DOI 10.14260/jemds/2015/1061
- Views 96
- Downloads 0
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