Asymptomatic Bacteriuria among Pregnant Women Attending Antenatal: Evaluation of Screening Test
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2015, Vol 5, Issue 8
Abstract
Introduction: Asymptomatic bacteriuria in pregnancy is common with a prevalence of 2 – 10% and is similar tothat observed among non–pregnant women. It is however more likely to progress to symptomatic urinary tract infection during pregnancy because of the physiological changes associated with pregnancy. The value of screening for asymptomatic bacteriuria in pregnancy cannot be over-emphasize, but the kits and methodology need to be evaluated before adoption. Methodology: The study was a prospective, cross sectional, hospital based study. All the subjects were given plastic universal sterile transparent container with screw cap and were enlightened to collect clean catch midstream urine for urinalysis dipstick and microscopy methods using a calibrated wireloop and tested against culture method (which was considered gold standard). RESULT: The urinary strip for nitrite gave a sensitivity of 25.0%, a specificity of 99.1% and a negative predictive value of 90.0% and positive predictive value of 80.0%. From the foregoing the false positive rate was 1.0% while the false negative rate was 10.0%. The efficacy of microscopy method was evaluated as evidence by the presence of pus cells and positive Gram’s stain (positive or negative Gram organism) and compared with gold standard culture, sensitivity (true positive) of 81.3%, a specificity of 94.5% was obtained. Conclusion: Microscopy method has appreciable sensitivity and specificity, biochemical methods have low sensitivities but high specificities when compared to the gold standard.
Authors and Affiliations
Dr Habiba Ibrahim Abdullahi , 2, Dr. Yunusa, Thairu
Keywords
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