BIOANALYTICAL METHOD VALIDATION – A REVIEW
Journal Title: Int J of Pharm Res & Analy - Year 2013, Vol 3, Issue 2
Abstract
The present review should extensively be discussed on an international level to reach a consensus on the extent of validation experiments and on acceptance criteria for validation parameters of bioanalytical methods in forensic clinical toxicology. The field of pharmacokinetic (PK) studies for registration of pharmaceuticals was discussed previously. Therefore, the most important analytical findings and validation parameters were discussed here
Authors and Affiliations
G. Balammal , G. Surendra , P. Jayachandra Reddy
VALIDATION OF STABILITY INDICATING HPLC METHOD FOR ASSAY OF FUSIDIC ACID, BETAMETHASONE-17 VALERATE AND CHLOROCRESOL CONTENT IN TOPICAL PHARMACEUTICAL FORMULATION
A new stability indicating reversed phase HPLC method was developed and validated for assay of fusidic acid, betamethasone -17 valerate and Chlorocresol in Topical pharmaceutical formulation. The chromatographic separati...
UTILITY OF ORAL AND VAGINAL MISOPROSTOL IN THE INDUCTION OF LABOUR: A COMPARATIVE STUDY
This study was conducted to compare the efficiency and safety of oral (50 μg) and vaginal (25 μg) misoprostol for labour induction. In this study one Hundred patients with indications for labour induction randomly...
DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR ESTIMATION OF LACOSAMIDE IN BULK AND ITS PHARMACEUTICAL DOSAGE FORM
A rapid and precise reverse phase high performance liquid chromatographic method has been developed for the validated of Lacosamide, in its pure form as well as in tablet dosage form. Chromatography was carried out...
METHOD DEVELOPMENT AND VALIDATION OF RP-HPLC ANALYSIS OF BROMFENAC IN RABBIT PLASMA
A simple, precise, rapid, and accurate reverse phase high performance liquid chromatography method was developed for the estimation of Bromfenac in Rabbit plasma by using Paracetamol as IS. The protein precipitation tech...
Spectrophotometric Estimation of Promethazine Hydrochloride In Bulk and Pharmaceutical Formulations
Two simple, accurate, rapid and sensitive methods (A and B) have been developed for the estimation of Promethazine Hydrochloride in its pharmaceutical dosage form. The method A and B are based on the formatio...