CLINICO-PATHOLOGICAL STUDY OF SKIN ADNEXAL TUMOURS IN A TERTIARY CARE HOSPITAL
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 47
Abstract
BACKGROUND Skin adnexal tumours are relatively uncommon tumours. They include a heterogeneous group of neoplasms showing morphological differentiation towards pilosebaceous unit, eccrine or apocrine structures. 1 AIM The aim of this study is to analyse the clinico-pathological features of various skin adnexal tumours from the medical records of the Department of Pathology in a tertiary care hospital. MATERIALS AND METHODS A retrospective 3 years clinico-pathological study of all skin adnexal tumours observed at our Institution from 2013 to 2015 was carried out. The clinical parameters and histopathological features of various histological types of skin adnexal tumours encountered were documented with review of literature. Fine Needle Aspiration Cytological (FNAC) details for certain available cases were also incorporated in the study. RESULTS Total number of skin adnexal tumours encountered in this study were 31 with maximum incidence among 31-40 years’ age group and Male:Female ratio of 1.06:1. Around 77% of skin adnexal tumours occurred in the Head and Neck region; 90.3% were benign and 9.7% were malignant tumours. Majority of these tumours were Eccrine tumours (51.6%) followed by Hair follicle tumours (29%), Apocrine (12.9%) and Sebaceous tumours (6.5%). Nodular hidradenoma was the most common benign skin adnexal tumour, while sebaceous carcinoma was the common malignant adnexal tumour encountered in this study. FNAC correlation was available for two cases of Nodular Hidradenoma and one case of malignant chondroid syringoma. Follow-up details were available for 21 cases. All the benign tumours showed complete cure following excision, while malignant chondroid syringoma showed local recurrence within 3 months of surgical excision. CONCLUSION The diagnosis of skin adnexal tumours is solely based upon histopathological examination. Owing to their varied lines of differentiation, overlapping morphological patterns and histological diversity they pose diagnostic challenge to the pathologists.
Authors and Affiliations
Karthik , Chitra , Arun
Keywords
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