EVALUATION OF IN VITRO ANTIOXIDANT AND GC/MS SPECTROSCOPIC ANALYSIS OF MEMECYLON UMBELLATUM BURM F FOR ITS BIOACTIVE COMPOUNDS
Journal Title: International Journal of Pharmaceutical Development & Technology - Year 2014, Vol 4, Issue 4
Abstract
ABSTRACT Medicinal plants plays a major role in the discovery of new therapeutic agents for drug development. In recent times there is more attention towards them, due to the presence of bioactive compounds and they have a dynamic role in prevention of various human diseases. Memecylon umbellatum Burm F (Family: Melastomataceae), is a traditional plant with potential ailing properties. In the present study, seed extracts of M. umbellatum were screened for phytochemicals using qualitative and quantitative analysis in order to discover and to improve the knowledge of traditional medicine. Based on phytochemical analysis, methanolic extract was evaluated for their In Vitro antioxidant potential and analyzed in GC-MS. Total antioxidant assay responded as well at 200 µg/mL, when compare to other solvent extracts methanol extract exhibited best activity. The highest total antioxidant capacity as BHT equivalents at 200 mg/g. Metal chelation effect of M. umbellatum displayed best activity in methanol extract 73.81% at 500 µg/mL GC-MS analysis revealed 8 major and minor phytochemical constituents in the methanolic seed extract of M. umbellatum. Keywords: Anjani, Methanol, GC-MS, Memecylon, Phytocomponents.
Authors and Affiliations
Kannan Elangovan, Dhanraj Priyanka, Suryamurthy Anupriya, Zahiruddin Shahin Banu Kandasamy Murugesan* CAS in Botany, University
Keywords
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