Hypokalemia paralyzing revealing a rare association of autoimmune diseases: type 1 diabetes, thyroiditis and tubulopathy about a case.
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2015, Vol 5, Issue 8
Abstract
Hypokalemia is a Paralyzing uncommon pathology, primitive often genetic autosomal dominant. Type 1 diabetes is an autoimmune disease of the pancreas responsible for a total deficit of insulinsecretion and hyperglycaemia. Someclinical manifestations extraglandular, canbe a discovery mode of the disease. We report the case of a patient with hypokalemiamoroccan Paralyzingrevealingthis pathology Whose combination with a renaltubulopathy by distal tubular acidosis (DTA) type 1 and autoimmune diseases of specific organ is rare. The DTA type 1 is related to the Inability of the distal tubule to secrete sufficient amount of hydrogen ions, making it possible to acidification of the urine below pH 5.5. This DTA is responsible for a severe rarely hypokalemia, neuromuscular complications, or revealing of a type 1 diabetes as is the case of our patient. A case of hypokalemiaparalyzingpuring a Sjögren syndrome (GSS) is associated with a thyroiditis was reported. Hypokalemia paralyzing revealing combination of autoimmune diseases annually (type 1 diabetes, thyroiditis and tubulopathy) isuncommon and difficulties to diagnose. Thus, faced with an unexplained hypokalemia neuromuscular paralysis in young patients, we must think although rare to a tubulopathy in the context of autoimmune diseases.
Authors and Affiliations
Matali Suzanne1 , Diarra Martin1, Tadmori Az Eddine1 , El Ouahabi Hanane1 , , Ajdi Farida1,2
Keywords
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