Moisturizing effect of stable cream containing Crocus sativus extracts
Journal Title: Pakistan Journal of Pharmaceutical Sciences - Year 2014, Vol 27, Issue 6
Abstract
The present study is about to prepare stable cream of water-in-oil emulsion containing extracts of Crocus sativus against its base (without extracts) taken as control, to determine its stability on different storage conditions and effects on skin moisture contents and transepidermal water loss. The formulation contains 3% Crocus sativus (Saffron) concentrated extracts, and the base containing no extract, were formulated. Different stability tests were done on samples, which placed at 8°C, 25°C, 40°C and 40°C with 75% relative humidity, for 4 week period. These formulations (Creams) were applied on the cheeks of human volunteers for 8week period. To evaluate any effect produced by these formulations different skin parameters were monitored every week. The significant results of this study explored the fact that water-in-oil emulsion topical cream of saffron formulated from Crocus sativus extract has absolute physical stability at different storage conditions. The increase in skin moisture contents and changes in transepidermal water loss were significant (p 0.05) with respect to base and formulation respectively. Topical cream of Crocus sativus showed significant moisturizing effects on human skin.
Authors and Affiliations
Naveed Akhtar , Haji Muhammad Shoaib Khan , Shoaib Ashraf , Imran Shair Mohammad , Najam-us-Saqib , Kamran Bashir
Keywords
Related Articles
- EP ID EP94635
- DOI -
- Views 98
- Downloads 0
Preparation, in-vitro and in-vivo characterization of transdermal patch containing glibenclamide and atenolol: A combinational approach
A novel aspiration in treatment of chronic disease like diabetes associated with other non communicable disease risk factors, such as hypertension is to provide greater therapeutic effect, overcome the side effects by co...
In vitro antimicrobial, antioxidant activity and phytochemical screening of Apium graveolens
The present study evaluates the phytochemical screenings, antioxidant activity and antimicrobial assay of Apium graveolens L. The phytochemical screening showed the presence of flavonoids, tannins, saponins and ste...
An approach for enhancing the production of human-like collagen II by enlarging the metabolic flux at pyruvate node
As a key metabolite of glycolysis, Pyruvate affects cell growth and metabolism directly. In order to enhance the production of human-like collagen (HLC) II, pyruvate was added into fermentation broth, and response...
Synthesis, characterization and antibacterial activity of colloidal NiO nanoparticles
The Colloidal solutions of nickel oxide (NiO) nanoparticles synthesized via Nd-Yag pulse ablation of nickel immersed in H2O were studied. The created nanoparticles were characterized by UV-VIS absorption, Fourier t...
Effect of phenological stages on nutritional assessment of ten plant species in Tehsil Takht-e-Nasrati, District Karak, Pakistan
The proximate analysis of ten plant species from Tehsil takht-e-Nasrati, district Karak was conducted at three phenological stages using standard techniques. The species showed variable results. In the test species...