MOSQUITO LARVICIDAL, OVIPOSITION DETERRENT AND REPELLENT PROPERTIES OF ACALYPHA ORNATA HOCHST. EX A. RICH. EXTRACTS AGAINST AEDES AEGYPTI, ANOPHELES STEPHENSI AND CULEX QUINQUEFASCIATUS
Journal Title: Asian J of Pharm Sci & Tech - Year 2015, Vol 5, Issue 2
Abstract
ABSTRACT The leaf extract of Acalypha ornata with different solvents viz., acetone, chloroform, hexane, petroleum ether and ethanol were tested for larvicidal, oviposition deterrent and repellent activities against the mosquitoes Aedes aegypti, Anopheles stephensi, and Culex quinquefasciatus. Larval mortality was observed and recorded after 24 h exposure period. In the present study, bioassay-guided fraction of A. ornata led to the separation and identification of a saponin as a potential mosquito larvicidal compound, with LC50 and LC90 value of 128.24, 230.40 ppm against Aedes aegypti, and 248.44, 447.19 ppm against An. stephensi and 228.6, 411.48 ppm against Cx. quinquefasciatus, respectively. In oviposition deterrent activity,the highest concentration of (0.1%) A. ornata produce (99.4%) against Aedes aegypti, 98.0% against Aedes aegypti and 97.5 % against Culex quinquefasciatus respectively. Skin repellent test at 0.02 ppm concentration of Acalypha ornatagives the complete protection time ranges from 68.4 to 122 minutes. The plant exerted the highest protection time of 126.2 minutes. GC-MS analysis data confirmed the identification of the active compound. This study investigates the potential of crude extracts from commonly used medical herbs in India as an environmentally safe measure to control the vector of dengue, malaria, and lymphatic filariasis. Key words: Acalypha ornata, Larvicide, Repellent, Filariasis, Malaria.
Authors and Affiliations
S. Ananth and P. Mani*
Keywords
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