Phytosome: A Brief Overview
Journal Title: Scholars Academic Journal of Pharmacy - Year 2013, Vol 2, Issue 1
Abstract
Abstract: In the recent days, most of the prevailing diseases and nutritional disorders are treated with natural medicines. Several plant extracts and phyto constituents, despite having excellent bioactivity in vitro demonstrate less or no in vivo actions due to their poor lipid solubility or improper molecular size or both, resulting in poor absorption and bioavailability. So, much work has been directed towards the development of new concept in herbal delivery system i.e., “phytosomes” which are better absorbed, utilized and as a result produce better results than conventional herbal extracts. Phytosomes often known as herbosomes. The term “phyto” means plant while “some” means cell-like. Phytosomes are little cell like structure. Phytosome is composed of phospholipids, mainly phosphatidylcholine, producing a lipid compatible molecular complex with other constituents. Phytosomal complexes were first investigated for cosmetic applications. But PHYTOSOME process was developed and petended by Indena, a leading supplier of nutraceutical ingredients like milk thistle, ginkgo biloba, grape seed, green tea, hawthorn, ginseng etc. Recently, green tea and one of its active components EGCG has received attention from major supplement brands for weight management supplements. Phytosomes are superior to liposomes due to Complex formation ratio of component and phospholipids is 2:1 and 1:1 respectively, much better absorption and stability profile. Phytosome is anti-inflammatory as well as antioxidant. In experimental animal models it improved resistance to atherosclerotic lesion development, enhanced a protective prostaglandin, and protected ventricular heart pump muscle against damage from circulatory deprivation. Development of phytosomes is at the budding stages in India and abroad. It has a lot of potential in the field of medicine, pharmaceuticals and cosmetics. Keywords : Phytosomes, medicine, Drug Development, Phospholipids
Authors and Affiliations
Sanjay Saha , Anupam Sarma , Pranjal Saikia , Tapash Chakrabarty
Keywords
Related Articles
- EP ID EP125502
- DOI -
- Views 109
- Downloads 0
Plants Possessing Potential Analgesic And Anti-Inflammatory Activities: A Review
Abstract – The side effects resulted due to the therapy of classical Non-steroidal anti-inflammatory drugs (NSAIDs) and the opoids in the management of pain and inflammatory conditions are major problems. Researche...
Antifungal and Phytochemical Screening of Hyptis suaveolens (L.Poit) Lamiaceae On Aflatoxin Producing Fungi
The present communication deals with the antifungal and preliminary phytochemical screening on the Hyptis suaveolens (L. Poit) Lamiaceae. The plant is stimulant, carminative, antispasmodic antirheumatic, antisuporitic ba...
Bisphenol A: Investigation and Prevention of Endocrine Disrupting in Albino Mice
Abstract: Bisphenol A (BPA) is an organic compound with the chemical formula C15H16O2 and is made from phenol and acetone.It is a colorless solid that is soluble in organic solvents, but poorly soluble in water, having t...
Antidiarrheal and Antimicrobial Activities of Ethno Medicinal Plant: Mikania scandens (L) Willd
Abstract: The aim of the present study was carried out to investigate the antidiarrheal and antimicrobial potential of both ethanol and aqueous extracts of aerial parts of Mikania scandens .In vivo Antidiarrheal activity...
Medicinal plants with anticancer effects (part 2)- plant based review
Herbal medicine is the oldest form of medicine known to mankind. It was the mainstay of many early civilizations and still the most widely practiced form of medicine in the world today. Plants generally produce many se...