Needle-tract bleeding after percutaneous radiofrequency ablation for hepatocellular carcinomas: risk factors,prevention and treatment
Journal Title: Di-er Junyi Daxue Xuebao - Year 2008, Vol 29, Issue 11
Abstract
Objective:To analyze the risk factors,prevention and treatment of needle-tract bleeding after percutaneous image-guided radiofrequency ablation (PRFA) for hepatocellular carcinomas (HCC).Methods: A total of 1 567 RFA sessions were performed on 1 203 patients with 3 067 focuses of hepatocellular carcinoma between December 1999 and January of 2008.The clinical data of patients suffering from needle-tract bleeding were analyzed for risk factors,prevention,and treatment.Results: Seventeen (1.08%,17/1 567) patients developed needle-tract bleeding.Univariate analysis showed that the incidence of needle-tract bleeding was significantly correlated with the lower platelet count,prolongation of prothrombin time,the degree of liver cirrhosis,subcapsular HCCs and pattern of RF needle electrode (P=0.039; P=0.023; P=0.012; P=0.032 and P=0.016,respectively).Logistic regression model found that only lower platelet count,prolongation of prothrombin time,degree of liver cirrhosis and subcapsular HCCs were the independent risk factors for needle-tract bleeding after PRFA in patients with hepatocellular carcinoma (OR=4.032,P=0.040;OR=5.611,P=0.009;OR=3.871,P=0.046 and OR=5.216,P=0.026,respectively).Of the 17 patients 5 received only medicine therapy in the internal department,4 received surgery and 10 received transcatheter embolization.Thirteen patients survived and 4 died.Conclusion: It is indicated that prolongation of prothrombin time,lower platelet count,sub-capsular HCCs and pattern of RF needle electrode can influence the needle-tract bleeding after PRFA in hepatocellular carcinoma patients.The most effective methods to control the bleeding are transcatheter embolization and DSA or surgery for HCC patients after PRFA.
Authors and Affiliations
Bo ZHAI
Keywords
Related Articles
- EP ID EP82931
- DOI -
- Views 99
- Downloads 0
基因组消减杂交技术筛选肾透明细胞癌转移相关甲基化基因
目的：筛选能够早期诊断和预测肾透明细胞癌转移相关基因的甲基化生物标志。方法：应用本室从临床新鲜组织标本体外培养建立的低转移性和高转移性肾透明细胞癌细胞株，病理学鉴定后提取基因组DNA，应用3轮NotⅠ基因组消减杂交的方法富集差...
Construction of PSAspecific dendritic cell vaccine and its in vitro immune activity
Objective:To construct of PSAspecific dendritic cell (DC) vaccine and to observe its in vitro antitumour activity, so as to pave a way for future study. Methods: Bone marrow precursors were isolated and bone marrow der...
胼胝体胶质瘤的显微手术及综合治疗策略
目的:探讨胼胝体胶质瘤的临床特点、显微手术可行性和术后综合治疗策略以改善预后。方法：回顾性分析1995年1月至2007年12月我院收治的82例胼胝体胶质瘤患者的临床特点、诊治经过及预后。术前根据影像特点选择最佳手术入路和切除的策略。术...
5α-双氢睾酮对前列腺癌LNCaP细胞钙离子移动和细胞生长的影响
目的:探讨5α-双氢睾酮(DHT)对前列腺癌LNCaP细胞钙离子移动的影响及其机制。方法:应用Fura-2/AM Ca2+ 荧光探针法结合MiraCal荧光成像系统动态检测DHT刺激以及Ca2+通道阻滞剂干预后LNCaP细胞内钙离子浓度([Ca2+]i)的变化。应用MTT法观察细...
TOPSIS analysis in evaluation of medical service quality in a Chinese hospital