Neourodynamics in patient with Alzheimer’s disease during working memory task
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 8
Abstract
Abstract:The aim of the present study was to evaluate the behaviour of memory-related electroencephalographic measures in patients with Amnesic Alzheimer’s disease. Electroencephalography (EEG) was recorded during working memory test (LB-memory test) in age-sex matched 30 normal elderly subjects and 20 amnesic Alzheimer’s disease patients (55-75 years). The EEG bands so evaluated were delta (0.2-3.9 Hz), theta (4.0-7.9 Hz), alpha (8.1- 12.9 Hz), beta (13.0 -30.0 Hz) and gamma (30.1-80 Hz). A significant decrease Mini Mental State Examination (MMSE) score was observed in patients when compared to controls (p=0.000). Amnesic Alzheimer’s patients showed significant decreased working memory scores in List A (p=0.038), List B (p=0.003) and List C (p=0.000), decreased absolute power in delta, theta, alpha, beta and gamma in fronto-central and temporal regions and significant decreased coherence in frontal (F3-F4) and temporal (T3-T4) lobes in alpha-1(8-9.9 Hz), alpha-2 (10-12.9 Hz) and beta (13-30 Hz) bands (p=0.000) during working memory task as compared to healthy, age and sex matched control subjects. These results suggest that absolute power and coherence during working memory task can discriminate Amnesic Alzheimer’s patients from normal elderly subjects. Keywords:AmnesicAlzheimer’s disease, Electroencephalography (EEG), Mini Mental State Examination (MMSE), working memory task, Absolute power, Coherence
Authors and Affiliations
Sweta Soni, Amitabh dube
Keywords
Related Articles
- EP ID EP373128
- DOI -
- Views 71
- Downloads 0
Phacoemulsıfıcation in Eyes with White Mature Cataract
The purpose of the study was to evaluate the results and complications of phacoemulsification surgery in eyes with white mature cataract. Sixty-three eyes of 63 patients with white mature cataract who had undergone phaco...
A descriptive study of emergency exploratory laparotomy cases operated at SMS hospital Jaipur
Despite being one of the most common urgent surgical procedures, emergency exploratory laparotomy still proves to be a challenge for the surgeons around the world. This study was done to present the clinico-demographic p...
A Study of Hemodynamic Response to Intubation with Suxamethonium and Org 9426 (Rocuronium)
Abstract: There is hemodynamic stress responses to tracheal intubation and can cause adverse cardiovascular events in patients with or without cardiovascular disease. The aim of the present study was to compare the intub...
Study on Elevated Maternal Serum Alpha-Fetoprotein in Second Trimester and Pregnancy Outcome
This study was a prospective observational study sponsored by DBT (Department of Biotechnology), New Delhi. It was carried out in Gauhati Medical College and Hospital during the period 2014-15 with a total of 202 women w...
Knowledge Attitude and Practices of Refuse Disposal in Abakaliki South East Nigeria
Abstract: Waste management is a global growing concern with public health consequences. In a developing country as ours, environmental laws are not entrenched and implemented. This makes improper waste disposal one of th...