Neurologic Signs due to Leptomeningeal Involvement as the Presenting Manifestation of Gastric Adenocarcinoma
Journal Title: Journal of Neurological Sciences-Turkish - Year 2006, Vol 23, Issue 4
Abstract
A 43-year-old female with a 5-month history of progressive neurological manifestations was admitted to our hospital. On examination, she was found to have multiple cranial nerve deficits and cerebellar syndrome. Laboratory investigations revealed a prominent increase in protein content with no significant pleocytosis in cerebro spinal fluid. Neuroimaging studies showed contrast enhancement on cerebellar cortex and leptomeningeal enhancement at brainstem. Although she had no complaints regarding gastrointestinal system, further investigatons led to the diagnosis of gastric adenocarsinoma. We report this case for the rare presentation of gastric adenocarcinoma with neurological manifestations due to leptomeningeal involvement.
Authors and Affiliations
Şebnem BIÇAKCI, Kezban ASLAN, Hacer BOZDEMİR, Kenan BIÇAKCI, Meltem DEMİRKIRAN, Murat ÖKSÜZ, Yakup SARICA
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