Neuromyelitis Optica Spectrum Disorder (NMOSD) in a Male with Hiccups and Quadriparesis
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 11
Abstract
Introduction: Neuromyelitis-optica (NMO)/ Neuromyelitis -optica spectrum disorders(NMOSD) is an inflammatory disease of central nervous system classically characterized by acute, severe episodes of optic neuritis and longitudinally extensive transverse myelitis (LETM), usually with a relapsing course. The identification of an autoantibody exclusively detected in NMO patients against aquaporin-4 (AQP-4) has allowed identification of cases beyond the classical phenotype. Atypical cases of NMO exist in scientific literature. These cases do not present with all the symptoms. Case Report: We present a case of a 53 year old female who presented to us with quadriparesis, intractable hiccups. MRI revealed longitudinally extensive transverse myelitis and later was diagnosed as a case of NMOSD. Conclusion: Neuromyelitis optica spectrum disorders (NMOSD) are inflammatory disorders of the central nervous system characterized by severe, immune-mediated demyelination and axonal damage predominantly targeting optic nerves and spinal cord. Serum NMO-IgG antibody is specific for the diagnosis.
Authors and Affiliations
Harshpreet Singh Tuteja, Ayush Somani, Sourya Acharya, Samarth Shukla
Keywords
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